摘要： Photo-controlled release that shows quick response and high spatial/temporal accuracy has become attractive given its potential applications for biomedicines. A few metal complexes are known for detoxification, sterilization, diagnosis and treatment of diseases; but, the encapsulation and control release of those metal ions using polymer micelles are challenging. We report an interesting photo-controlled release of metal ions via photo-responsible triazoline-containing amphiphilic polymers. Amphiphilic random copolymers of glycidyl methacrylate and oligo(ethylene oxide) methyl ether methacrylate were prepared through free radical copolymerization. The glycidyl pendants were converted to azide, followed by a 1,3-dipolar cycloaddition reaction to form triazoline with norbornene. The resulting random copolymers containing triazoline formed micelles with a critical micellar concentration (CMC) of 7.68×10-3 mg/mL. The triazoline moieties could coordinate to transition metal ions, e.g. Co2+, thus to encapsulate the metal ions to the core of micelles. Photo-induced denitrogenation of triazoline was able to disrupt the coordination of Co2+ and triazoline, therefore leading to the release of Co2+. Solution viscosity, UV-vis/NMR spectroscopy and TEM were used to show that the coordination and release of Co2+ ions were successful upon exposure to light. The photo-controlled release profile was found to be linearly dependent on the irradiation time, which is potentially useful for the delivery of essential ions in vivo.