摘要： Nanostructures research plays a crucial role in the transformation of breakthrough scientific ideas into next-generation technology. In the way that silicon revolutionized the microelectronics industry, plasmonic nanostructures can greatly impact on the field of analytical instruments for molecular analysis of materials, even biological objects. Currently, research in the plasmonics has been faced the problem of choosing the optimal plasmonic nanostructures in order to realize useful devices. Usually, metal components such as gold, silver and copper serve for working elements of plasmon-active surfaces, which have a number of advantages in comparison with other materials. However, on the stage of devises design, the choice even between three different metals causes great difficulties. In order to take the first steps to solve this problem, here we consider the criteria for plasmon-active metals choice, and also give examples of Au, Ag, and Cu nanostructures obtained by the controlled self-assembly in limited pore volume of the SiO2/Si template for SERS applications.