研究目的
To compare the outcomes of standard pop-titrated transscleral cyclophotocoagulation (TSCPC) and slow-coagulation TSCPC in the treatment of glaucoma.
研究成果
In this case series, slow-coagulation TSCPC and standard pop-titrated TSCPC resulted in similar VA and IOP outcomes in the treatment of glaucomatous eyes. The complication profiles of the techniques also were comparable, although standard TSCPC showed a higher incidence of prolonged inflammation after surgery. This study suggests that slow-coagulation TSCPC may achieve equivalent control of IOP while reducing the incidence of prolonged postoperative inflammation—a feared complication of TSCPC—when compared with standard pop-titrated TSCPC.
研究不足
1. Its retrospective nature introduces potential sources of bias. 2. The end-stage nature of most eyes included in the study precludes the application of the results to the large population of glaucoma patients who maintain more functional vision. 3. Its reliance on proper documentation in the medical record for detailed procedural reports and for outcome measures such as postprocedural inflammation and pain. 4. The fact that the study is underpowered to detect small but potentially significant differences in a number of the outcome measures.
1：Experimental Design and Method Selection:
A retrospective chart review was performed of patients who underwent diode TSCPC at the Bascom Palmer Eye Institute from July 1, 1995, through June 30,
2：The study compared 52 eyes treated with slow-coagulation TSCPC with 26 eyes treated with standard pop-titrated TSCPC. Sample Selection and Data Sources:
20 Patients with glaucoma of any type or stage that underwent TSCPC as part of their treatment course were included. Exclusion criteria included major charting deficiencies and loss to follow-up before 6 months after TSCPC.
3：List of Experimental Equipment and Materials:
Diode laser was applied to the ciliary body using the G-Probe after topical and injected periocular anesthesia.
4：Experimental Procedures and Operational Workflow:
For application of standard coagulation, a starting power of
5：75 W and a 0-second duration were used, and the laser energy was titrated such that the minimum power required to produce a pop was applied. The slow-coagulation method was conducted according to a technique proposed by Gaasterland. Data Analysis Methods:
Data collection included patient demographics, treatment course, surgical techniques, and outcomes. Outcomes of interest included visual acuity (VA), intraocular pressure (IOP), and postprocedural complications.
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