研究目的
To compare the effect of visible LLLT and microcurrent therapy on burn wound healing in Wistar rats using histological analysis.
研究成果
LLLT (AlGaInP 660 nm) and microcurrent (160 μA) accelerated the healing in burned tissue in Wistar rats, with microcurrent therapy showing faster tissue repair evidenced by the presence of cutaneous appendages. Further studies are needed to compare the two therapies more comprehensively.
研究不足
The study was limited to a 10-day treatment period, which may not be sufficient for total tissue regeneration. Different laser parameters and microcurrent amperage may influence organic responses, requiring further studies to define optimal settings.
1：Experimental Design and Method Selection:
A randomized controlled study with 30 Wistar rats divided into 3 groups (n = 10); control group (CG), laser group (LG) and microcurrent group (MG). After thermal damage, 10 applications of 660 nm diode laser were performed in GL and 10 applications of 60 Hz microcurrent (160 μA) in MG.
2：Sample Selection and Data Sources:
30 Wistar rats, weighing approximately 250 to 300 grams.
3：List of Experimental Equipment and Materials:
Low-level laser (AlGaInP, 660 nm), microcurrent stimulator (Bioset?), adhesive electrodes (Valutrode?
4：2 cm2 diameter), anesthetic tiletamine-zolazepam (Zoletil?), aluminum plate. Experimental Procedures and Operational Workflow:
After thermal damage, treatments were applied daily for 10 days. Histological analysis was performed on the healing tissue.
5：Data Analysis Methods:
Semi-quantitative histological analysis using scores (0–3), Kruskal-Wallis test, Dunn’s Multiple Comparison Post-Test.
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