研究目的
To determine the safety and efficacy of fractional ablative erbium-doped yttrium aluminium garnet (Er:YAG) laser in the treatment of hypertrophic burn scars.
研究成果
Fractional ablative Er:YAG laser treatment is a safe and effective modality for improving hypertrophic scars, with significant improvements in dyschromia, hypertrophy, vascularity, and texture.
研究不足
The study is a pilot with a small sample size of 11 subjects. The 3-month follow-up period is short for scar evaluation, and longer-term effects are not assessed.
1:Experimental Design and Method Selection:
A prospective pilot study was conducted to evaluate the efficacy of 2,940-nm ablative fractional erbium:YAG laser for hypertrophic scars.
2:Sample Selection and Data Sources:
Eleven subjects aged 18 to 75 years with history of traumatic burn injury resulting in severe hypertrophic burn scars were selected.
3:List of Experimental Equipment and Materials:
Fractional ablative Er:YAG laser (Sciton, Inc., Palo Alto, CA), Nikon D300 camera.
4:Experimental Procedures and Operational Workflow:
Patients were treated 3 times with the laser at 400 to 800 mm, density 11%, no coagulation, single pass at 4-week intervals.
5:Data Analysis Methods:
Blinded evaluation of before and after photographs using a modified Manchester quartile scale.
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