研究目的
To report the successful treatment of advanced keratoconus in a child's eye through femtosecond laser–assisted intrastromal corneal lenticule implantation, aiming to thicken and flatten the cornea and postpone the need for corneal transplantation.
研究成果
Femtosecond laser–assisted intrastromal corneal lenticule implantation was successful in thickening and flattening the cornea of a child with advanced keratoconus, potentially postponing the need for corneal transplantation to a more suitable age. The procedure improved corneal curvature and visual acuity, demonstrating its feasibility and safety in this challenging case.
研究不足
The study is limited by being a single case report, which may not be generalizable to all patients with advanced keratoconus. Long-term outcomes and the need for further interventions like corneal transplantation remain to be evaluated.
1：Experimental Design and Method Selection:
A case report of a 12-year-old male patient with advanced keratoconus treated with femtosecond laser–assisted intrastromal implantation of a donor corneal lenticule.
2：Sample Selection and Data Sources:
The patient's left eye with advanced keratoconus was selected for the procedure. Preoperative and postoperative data including UDVA, refraction, corneal topography, and tomography were collected.
3：List of Experimental Equipment and Materials:
Femtosecond laser (Femto LDV Z8 Ziemer Ophthalmic Systems AG), donor cornea, riboflavin (Mediocross), UV light (IROC Innocross AG), Optsol-GS (Bausch & Lomb, Inc.), moxifloxacin (Vigamox).
4：Experimental Procedures and Operational Workflow:
Donor corneal lenticule preparation involved deepithelialization, crosslinking with riboflavin and UV light, and femtosecond laser cutting. The lenticule was then implanted into a pocket created in the patient's cornea using the femtosecond laser.
5：Data Analysis Methods:
Postoperative follow-ups included biomicroscopy, pachymetry, topography, and tomography to assess corneal clarity, thickness, and curvature.
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