研究目的
To functionalize the surface of bulk polyethylene (PE) by coating it with activated silicon nitride (Si3N4) powder to protect the polymer from oxidation while conferring both antibacterial and osteogenic properties.
研究成果
The Si3N4 laser-cladded coating process successfully transferred the beneficial biological properties of bulk Si3N4 to PE, providing both antibacterial and osteoconductive properties. This technology could improve the performance of polyethylene-based medical devices.
研究不足
The Si3N4 particles did not penetrate deeply into the PE matrix, and their distribution was non-uniform across the surface. The antibacterial effect was more pronounced after long-term exposure.
1：Experimental Design and Method Selection:
A pulsed Nd:YAG laser was used to clad polyethylene with silicon nitride powder in a nitrogen gas atmosphere to prevent oxidation.
2：Sample Selection and Data Sources:
Low-density polyethylene pellets were used to prepare substrates, and Si3N4 powder was provided by SINTX Technologies Corporation.
3：List of Experimental Equipment and Materials:
Vision LWI VERGO-Workstation Nd:YAG laser, Raman spectroscopy (T-64000, Jobin-Ivon/Horiba Group), confocal scanning laser microscope (Keyence, VKx200 Series), SEM and EDS (JSM-700 1F, JEOL).
4：Experimental Procedures and Operational Workflow:
PE substrates were prepared by melting and molding, then coated with Si3N4 powder using laser cladding. Surface characterization was performed using Raman spectroscopy, laser microscopy, SEM, and EDS. Biological testing included antibacterial assays against Staphylococcus epidermidis and osteoconductivity tests with SaOS-2 osteosarcoma cells.
5：Data Analysis Methods:
Raman spectra were analyzed using LabSpec software. Surface roughness was measured and averaged over 25 random locations. Biological assay data were analyzed for bacterial viability and cell proliferation.
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