研究目的
To predict the propagation velocity of different concentrations of bovine serum albumin (BSA) in a Rayleigh-type biosensor and evaluate the effect of these concentrations.
研究成果
The propagation velocity of the SAWs is largely related to the liquid concentration. The Rayleigh-type SAW device can identify different concentrations of BSA. The 0.40 mm width-0.25 mm height groove was more suitable than the 0.25 mm width-0.26 mm height groove for studying the propagation velocity of wave with liquid in a Rayleigh-type SAW device. The propagation velocity decreased when the concentration of BSA protein increased.
研究不足
The size of groove also affects the propagation velocity. The theoretical formula for calculating the velocity from the concentration was not derived. The research is based on limited size of the groove.
1：Experimental Design and Method Selection:
Derived a new calculation method for a Rayleigh surface acoustic wave (SAW) device to calculate propagation velocities of leaky Rayleigh waves and Rayleigh waves when liquid is placed in the groove of a Rayleigh-type SAW device.
2：Sample Selection and Data Sources:
Used different concentrations of BSA proteins and a Rayleigh-type SAW device with specific groove sizes and quartz as the substrate.
3：List of Experimental Equipment and Materials:
Rayleigh-type SAW device with grooves of
4：25 mm width and 26 mm height and grooves of 40 mm width and 25 mm height, quartz substrate, interdigital transducers (IDT) with a 00 mm distance. Experimental Procedures and Operational Workflow:
Set the frequency of the Rayleigh-type SAW device to
5：6 MHz, measured the propagation velocity of SAWs with different concentrations of BSA proteins in the grooves. Data Analysis Methods:
1 Analyzed the effect of BSA protein concentration and groove size on the propagation velocity of SAWs.
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