研究目的
To evaluate the usefulness of NIRSIT as an fNIRS device for the early detection of stroke.
研究成果
NIRSIT (an fNIRS device with 204 channels) might help with the early recognition of stroke without the use of radiation or contrast agents by reflecting differences in the oxygen saturation levels in the bilateral frontotemporal lobes. NIRSIT may be easily applied in the ED and at the pre-hospital stage, thus facilitating the early detection of stroke, the transfer of patients to the appropriate institution, and early intervention.
研究不足
1. The sample size was small because this was a pilot study. 2. The device was attached to the forehead and detected the rSO2 of the area, not reflecting the lacunar part of the infarction in the basal ganglia or the posterior circulation of the brain. 3. The measurements did not present cerebral hemorrhage. 4. The sensors of NIRSIT cover the frontotemporal area, not the whole brain. 5. NIRSIT was not applied after thrombolysis or thrombectomy.
1：Experimental Design and Method Selection:
A prospective pilot study was conducted in an emergency department (ED) to compare fNIRS to conventional PCT and PWI.
2：Sample Selection and Data Sources:
Adult patients with suspected symptoms and signs of stroke within 12 h of the ?rst abnormal time and who underwent intravenous thrombolysis (IVT) or intra-arterial thrombectomy with acute middle cerebral artery (MCA) or internal carotid artery (ICA) infarction were enrolled.
3：List of Experimental Equipment and Materials:
NIRSIT, a wearable fNIRS device with 204 channels, was used to measure HbO2, HbR, and rSO
4：Experimental Procedures and Operational Workflow:
NIRSIT was applied to the patient's forehead during the neurological examination and during the preparation time for the transfer of the patient from the ED to the computed tomography or magnetic resonance imaging room.
5：Data Analysis Methods:
The NIRSIT results were compared with the MTT map from PCT and the TTP map from PWI.
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