研究目的
To develop a flexible adhesive bandage sized near infrared spectroscopy system (pediBand) for home-assessment of apnea in children with Down syndrome.
研究成果
The miniaturized pediatric NIRS polysomnography system (pediBand) is a promising tool for caregivers to use to study and improve the health of their pediatric Down syndrome patients. Future work will include clinical validation of oxygenation measurements for pediBand based NIRS to recognize physiological signals associated with sleep apnea in pediatric patients with DS.
研究不足
The study presents a proof of concept with a modified version of the system applied to adult subjects. Clinical validation for pediatric patients with Down syndrome is pending.
1：Experimental Design and Method Selection:
The study involves the development of a miniaturized NIRS system combined with inertial measurement units to monitor physiological signals related to sleep apnea.
2：Sample Selection and Data Sources:
The system was evaluated on adult patients to demonstrate its capability in detecting changes in the hemodynamic system triggered by sleep apnea.
3：List of Experimental Equipment and Materials:
The system includes commercial off the shelf system-on-chip microcontrollers with embedded Bluetooth transceivers, a Si1143 light sensor, and a MXC6255XU accelerometer.
4：Experimental Procedures and Operational Workflow:
The device was tested in a sleep laboratory to compare its measurements with traditional PSG systems.
5：Data Analysis Methods:
The modified Beer-Lambert Law was used to calculate the relative concentration of hemoglobins.
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