研究目的
To discuss the interpretation of corneal stromal demarcation lines after different corneal crosslinking protocols and the factors influencing CXL efficacy.
研究成果
The letter concludes that while the demarcation line may indicate some aspects of CXL efficacy, it is not the sole determinant, and factors like oxygen diffusion and epithelial viability play significant roles. It also highlights the potential of new in vivo means to measure corneal stiffness, such as Brillouin microscopy, to further elucidate these questions.
研究不足
The letter points out the difficulty in interpreting the demarcation line in images and suggests that oxygen availability and epithelial viability are critical factors not fully accounted for in the original study.
