摘要： Stress causes various types of physical disorders. When we experience stress, vital signs change as the sympathetic nervous system works to respond to stress and cope with the stressor. To prevent the disorders associated with stress, it is important to be able to measure multiple vital signs using a non-invasive method in order to detect the occurrences that cause these disorders in our daily lives. This study aimed to develop an integrated non-invasive vital signs monitoring system to measure vital signs such as heart rate variability and alterations in skin temperature, and to assess the ability of the system to detect stress. We developed an algorithm to measure pulse rate with high accuracy, on the basis of near infrared images of the human cheek, and we measured the nasal and forehead skin temperatures based on far infrared images. In the experiments, the system was demonstrated to calculate a pulse rate with sufficient accuracy. In addition, we conducted a stress detection experiment with four human participants, and we confirmed that the proposed integrated system could effectively detect stress, on the basis of the measured pulse rate and skin temperature, as stimulated by cold water applied to the wrist. In conclusion, the developed system was validated to be a feasible means of detecting stress.