研究目的
Investigating the non-neuronal evoked and spontaneous hemodynamic changes in the anterior temporal region of the human head and their potential to lead to misinterpretations of functional near-infrared spectroscopy signals.
研究成果
The study concludes that examining individual components of hemoglobin signal alone can lead to misinterpretation of fNIRS findings, emphasizing the importance of reporting results based on both O2Hb and HHb for proper interpretation, especially in the anterior temporal region. Inclusion of short-distance measurement channels is suggested to improve results interpretation.
研究不足
The study's limitations include the mean population age assessed, absence of direct measures of muscle activity, and the absence of short-distance measurement channels to separate extracortical information from cortical signals.
1:Experimental Design and Method Selection:
The study assessed the correlation between [O2Hb] and [HHb] in task-evoked activity and resting-state data using continuous-wave NIRS systems.
2:Sample Selection and Data Sources:
Two datasets were used: one for task-evoked activity and another for resting-state activity, collected from participants with specific instructions.
3:List of Experimental Equipment and Materials:
Continuous-wave NIRS systems (ETG-4000, Hitachi Medical Corporation, and NIRScout, NIRx Medical Technologies) with specific wavelengths for intensity data acquisition.
4:Experimental Procedures and Operational Workflow:
Data were collected under specific conditions, filtered, and analyzed for correlation between chromophores.
5:Data Analysis Methods:
Spearman’s correlation coefficient was used to assess the relationship between [O2Hb] and [HHb], with additional metrics like blood volume pulse amplitude and channel-wise correlation for further analysis.
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