研究目的
To review and evaluate clinical practices of imaging and therapy, particularly combinations of multimodality imaging and therapy, with the goal of lessening human suffering through enhanced efficacy and reduced toxicity in cancer treatment.
研究成果
Multimodality image-guided treatment represents a rapidly evolving field with the potential to significantly improve cancer therapy by enhancing targeting accuracy and reducing toxicity. Successful deployment requires clear definition of therapy goals, accurate image fusion, reliable tracking devices, and overcoming economic and regulatory barriers.
研究不足
The chapter highlights technical and application constraints, including the need for simultaneous image acquisition for accurate registration, the challenge of defining tumor volumes across different modalities, and the high cost and regulatory hurdles of developing and deploying MIGT technologies.
1：Experimental Design and Method Selection:
The chapter reviews current practices and experimental stages of multimodality image-guided treatment (MIGT), including the use of SPECT-CT, PET-CT, and PET-MRI for tumor localization and therapy guidance.
2：Sample Selection and Data Sources:
Clinical and experimental data from cancer patients and animal models are discussed, focusing on tumor localization and treatment efficacy.
3：List of Experimental Equipment and Materials:
Includes imaging modalities like US, CT, MRI, SPECT, PET, and therapeutic devices such as Gamma Knife, proton beam therapy, and radiofrequency ablation (RFA) equipment.
4：Experimental Procedures and Operational Workflow:
Describes the integration of imaging modalities for tumor localization and the use of robotics and software for precise therapy delivery.
5：Data Analysis Methods:
Discusses the use of imaging parameters for tumor characterization and treatment monitoring, including RECIST and PERCIST criteria.
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