研究目的
To review the progress and perspectives of composite materials in the form of thin films based on renewable resources for biofabrication of a new generation of medical implants with antibacterial properties.
研究成果
The chapter concludes that advanced laser techniques like MAPLE and C‐MAPLE are viable fabrication methods for a new generation of metallic implants, offering multifunctional structures with combined bioactive osteoinductive and antimicrobial action. These techniques allow for the conservation of biomaterial composition, structure, morphology, and functionality, making them suitable for various biomedical applications.
研究不足
The study acknowledges the limitations of current deposition methods in terms of coating thickness, multilayer deposition, adherence, composition, or crystallinity. It also highlights the challenges in the development and utilization of secondary metabolites of plants as substitutes to traditional antibiotics.
1：Experimental Design and Method Selection:
The study focuses on the use of advanced laser techniques, specifically matrix‐assisted pulsed laser evaporation (MAPLE) and Combinatorial‐MAPLE, for the synthesis of composite coatings based on renewable resources like chitosan and lignin.
2：Sample Selection and Data Sources:
The research utilizes renewable biomaterials such as chitosan and lignin, focusing on their properties and applications in biomedical fields.
3：List of Experimental Equipment and Materials:
A pulsed KrF* laser source (λ = 248 nm, ζFWHM = 25 ns) operating at 10 Hz was used for the evaporation of composite frozen targets. Pure titanium foils or silicon wafers were used as substrates.
4：Experimental Procedures and Operational Workflow:
The deposition process involved adjusting parameters like laser wavelength, laser fluence, repetition rate, solvent type, solute concentration, substrate temperature, and background gas nature and pressure to ensure the biomaterial is deposited without considerable decomposition.
5：Data Analysis Methods:
The synthesized structures were subjected to analysis by scanning electron microscopy (SEM), energy‐dispersive X‐ray spectroscopy (EDS), X‐ray diffraction analysis (XRD), X‐ray photoelectron spectroscopy (XPS), and attenuated total reflectance‐Fourier transform infrared (ATR‐FTIR).
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