研究目的
Investigating the link between coronary spasms, intraluminal thrombus formation, and widespread organized and layered thrombi in heart-transplanted (HTx) patients, and evaluating the clinical value of optical coherence tomography (OCT) in these patients.
研究成果
The case highlights the potential link between coronary spasms and complex layered thrombotic plaques in HTx patients. OCT provides high-resolution vessel imaging that may be beneficial in detecting mural thrombi not visible by coronary angiography. The clinical significance and mechanisms of these findings warrant further evaluation.
研究不足
The study lacks histological validation of OCT findings. Future histological studies should address if layered complex plaques are associated with organized thrombosis.
1:Experimental Design and Method Selection:
The study presents a case report of a 19-year-old HTx patient with acute myocardial infarction induced by severe coronary spasms. OCT was used for high-resolution vessel imaging.
2:Sample Selection and Data Sources:
The patient was selected based on hospitalization due to acute myocardial infarction and suspected coronary spasms. Data sources include electrocardiogram, coronary angiography, and OCT.
3:List of Experimental Equipment and Materials:
Optical coherence tomography (OCT) was used for intravascular imaging.
4:Experimental Procedures and Operational Workflow:
The patient underwent coronary angiography and OCT to assess coronary spasms and thrombus formation. Percutaneous coronary intervention was performed to stabilize the patient.
5:Data Analysis Methods:
The findings from OCT and coronary angiography were analyzed to assess the presence of thrombi and coronary spasms.
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