研究目的
Investigating the impact of metastatic melanomas on the optical parameters of artificial human skin tissue using Terahertz Time Domain Spectroscopy (THz-TDS) to aid in early tumor diagnosis and prevention.
研究成果
Artificial skin samples with metastatic melanomas exhibit higher refractive indexes and absorption coefficients than normal samples due to increased water content. This finding can contribute to the development of early tumor diagnosis and prevention techniques.
研究不足
The study is preliminary and focuses on artificial skin samples. The contrast mechanism between normal and diseased tissues is not fully understood. The study is limited to a specific frequency range (0.2 THz to 1.6 THz).
1：Experimental Design and Method Selection:
The study uses THz-TDS to compare the optical parameters of artificial skin tissues with and without metastatic melanomas.
2：Sample Selection and Data Sources:
Artificial skin samples were prepared with a standard collagen mixture, with and without WM1158 melanoma cells.
3：List of Experimental Equipment and Materials:
THz-TDS setup, type I collagen, Minimum Essential Medium (MEM), Fetal Bovine Serum (FBS), RPMI medium, TPX plates.
4：Experimental Procedures and Operational Workflow:
Samples were prepared, incubated, and measured using THz-TDS in transmission mode. Data were collected and analyzed to determine refractive indexes and absorption coefficients.
5：Data Analysis Methods:
Fourier transformation was performed on time domain signals to recover phase and amplitude information. Refractive index and absorption coefficient were calculated using provided equations.
独家科研数据包，助您复现前沿成果，加速创新突破
获取完整内容
