研究目的
To clarify whether small-diameter brain PET systems can achieve higher NECR compared with large-diameter brain PET system and whole-body PET system.
研究成果
The small-diameter brain PET system with conventional electronics has limited advantage on NECR for clinical studies, but with advanced electronics, it can achieve higher NECR than whole-body PET systems, making it useful for clinical use.
研究不足
The study used a single non-paralyzable dead-time model which may not accurately reflect experimental count rate characteristics. The number of group encoders was the same for all PET systems, which may not represent the typical configuration where the number increases with ring diameter.
1：Experimental Design and Method Selection:
Monte Carlo simulation based on the Geant4 toolkit (version
2：2) was used to evaluate the count rates of PET systems with different ring diameters. Sample Selection and Data Sources:
Simulated PET systems were configured like a previously developed PET system for validation.
3：List of Experimental Equipment and Materials:
The scintillator used was Lu
4：9Gd1SiO5 (LGSO) with a thickness of 15 mm. The energy resolution was 14% FWHM. Experimental Procedures and Operational Workflow:
Observed single count rate and coincidence count rate were calculated using analytical calculation for count losses and dead-time.
5：Data Analysis Methods:
NECR and scatter fraction were calculated to compare the performance of PET systems with different diameters and electronics.
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