研究目的
To evaluate current reported patient radiation exposure from nuclear laboratories in the United States applying for Intersocietal Accreditation Commission accreditation for myocardial perfusion imaging using single photon emission computed tomography or positron emission tomography.
研究成果
Cardiac PET MPI has low radiation exposure (3.7 mSv) and is below ASNC recommendations, while SPECT MPI has higher exposure (12.8 mSv) with few laboratories meeting goals. PET is preferred for pharmacological MPI testing, and radiation reduction strategies for SPECT are underutilized.
研究不足
Relies on self-selected data from laboratories seeking accreditation, may not represent all studies; radiation exposure is an approximation; PET camera type (2D or 3D) not recorded; additional radiation from attenuation correction not included; limited to MPI studies, not other nuclear cardiology protocols.
1:Experimental Design and Method Selection:
Analysis of data submitted to the Intersocietal Accreditation Commission (IAC) for accreditation, using statistical tests (χ2 and Mann-Whitney U tests) to compare radiation exposure between PET and SPECT MPI.
2:Sample Selection and Data Sources:
Data from 665 SPECT facilities in 2015 and 111 PET facilities from 2013 to 2015, with 3067 SPECT and 532 PET studies.
3:List of Experimental Equipment and Materials:
Not specified in detail, but involves radiopharmaceuticals (e.g., thallium-201, technetium-99m, rubidium-82, ammonia N-13) and imaging systems (PET and SPECT cameras).
4:Experimental Procedures and Operational Workflow:
Calculation of radiation exposure based on reported radioisotope amounts using International Commission on Radiological Protection compendium, with effective dose conversion.
5:Data Analysis Methods:
Statistical analysis using SPSS version 25.0, including descriptive statistics, χ2 tests, Mann-Whitney U tests, Kruskal-Wallis tests, and Spearman correlation.
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