研究目的
To examine the impact of light intensity and temperature on reading performance following bilateral pseudophakic multifocal presbyopic correction.
研究成果
Multifocal pseudophakic corrections improve reading ability but vary with light conditions. Trifocal lenses provide superior, light intensity-independent performance except at cold temperatures, while bifocal lenses are light-dependent. Monofocal corrections have poor reading ability without spectacles. Lighting recommendations should be revised for optimal performance.
研究不足
No randomization among multifocal groups due to lifestyle-dependent selection; strict enrollment criteria for pupil dilation and centroid shift may not generalize to all patients; further studies with larger cohorts and evaluation of other activities needed.
1:Experimental Design and Method Selection:
Prospective, nonrandomized controlled study adhering to the Declaration of Helsinki. Reading ability was assessed using the Greek version of the MNREAD chart under various light conditions (intensities of 25, 50, 75 FC and temperatures of 3,000, 4,000, 6,000 K). Statistical analyses included normality tests, t-tests, ANOVA, Mann-Whitney U-test, and multiple linear regression.
2:Sample Selection and Data Sources:
75 patients divided into three groups (G1: bifocal IOL, G2: trifocal IOL, CG: monofocal IOL) based on inclusion criteria (senile cataract stage 2 or 3, no astigmatism >1.00 D, etc.) and exclusion criteria (glaucoma, prior surgery, etc.). Data collected at the University Hospital of Alexandroupolis, Greece.
3:00 D, etc.) and exclusion criteria (glaucoma, prior surgery, etc.). Data collected at the University Hospital of Alexandroupolis, Greece. List of Experimental Equipment and Materials:
3. List of Experimental Equipment and Materials: MNREAD-GR chart, simulation room with adjustable lighting, Wavelight Topolyzer Vario for pupil measurements, handheld light meter (Topwor-US, Sunche HS1010), Alcon Infinity VisionSystem for surgery, Verion Digital Marker System, various ophthalmic devices and lenses (e.g., ReSTOR, PanOptix, AcrySof IQ SF60WF).
4:Experimental Procedures and Operational Workflow:
Pupil measurements in dark room, surgical procedures performed consistently, reading assessments at 40 cm distance with minimal speed of 80 words/min under nine light combinations, subjective preference recording.
5:Data Analysis Methods:
Shapiro-Wilk test for normality, Student's t-test, ANOVA, Mann-Whitney U-test, multiple linear regression using Medcalc software.
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ReSTOR intraocular lens
ReSTOR (add +2.50)
Alcon Laboratories, Inc.
Bifocal hybrid intraocular lens for presbyopic correction
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MNREAD chart
Greek version (MNREAD-GR)
Minnesota Low Vision Laboratory
Assessment of near visual acuity and reading ability
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Wavelight Topolyzer Vario
Not specified
Alcon Research
Dynamic pupil measurement, evaluation of pupil centroid shift and diameter
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Handheld light meter
HS1010
Sunche
Measurement of illuminance values
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Alcon Infinity VisionSystem
Not specified
Alcon
Surgical platform for cataract surgery
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Verion Digital Marker System
Not specified
Alcon
Guidance for surgical incisions to minimize astigmatism
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PanOptix intraocular lens
PanOptix
Alcon Research
Trifocal diffractive intraocular lens for presbyopic correction
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AcrySof IQ SF60WF intraocular lens
SF60WF
Alcon Research
Monofocal intraocular lens for control group
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Ophthalmic Viscosurgical Devices
Viscoat, Hiluron
Alcon, Vadodara
Used during surgical procedures
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