1：Experimental Design and Method Selection:

Retrospective multicentric study analyzing data from bilateral non-sequential lens surgery with implantation of a diffractive trifocal intraocular lens (FineVision Micro F12, PhysIOL). The study followed the principles of the Declaration of Helsinki and was approved by the Medical-Legal Commission of Clínica Baviera.

2：Sample Selection and Data Sources:

Included 5,186 patients (10,372 eyes) who underwent refractive or cataract lensectomy with trifocal IOL implantation, with at least 3 months of follow-up. Exclusion criteria included amblyopia, history of refractive or corneal surgery, corneal disease, endothelial dystrophy, retinal detachment history, neuro-ophthalmic disease, pregnancy/lactation, and intra- or postoperative complications affecting visual or refractive outcomes. Data were obtained from Clínica Baviera's automated central clinical record system.

3：List of Experimental Equipment and Materials:

Equipment included slit lamp, intraocular pressure measurement tools, tear break-up time (T-BUT) assessment, pupillometry, pachymetry, funduscopy, endothelial cell count (SP 3000P; Topcon), optical biometry by interferometry (IOLMaster, Carl Zeiss Meditec AG), immersion ultrasound biometry (Ocuscan RPX; Alcon), corneal topography (Orbscan II, Bausch & Lomb; PENTACAM, Alcon), and ocular computed tomography of the macular area. The IOL used was FineVision Micro F12 (PhysIOL).

4：Experimental Procedures and Operational Workflow:

Surgeries were performed by 48 surgeons in 25 centers using identical protocols, including corneal incision, capsulorhexis, phacoemulsification, IOL implantation in the capsular bag, and intracameral cefuroxime injection. Postoperative treatment included topical antibiotic and steroid combinations. Patients were evaluated at 24 hours, 5-7 days, 1 month, and 3 months post-surgery.

5：Data Analysis Methods:

Descriptive analysis of biometric parameters using means and standard deviations. Statistical calculations were performed with STATA 13 software. Pre- and postoperative results were compared using paired t-tests after normality checks, with p < 0.05 considered significant.