研究目的
To propose an algorithm for kidney arterial system segmentation and a methodology for preparing patient-specific 3D models to facilitate preoperative planning and intraoperative support in percutaneous nephrolithotomy (PCNL) procedures.
研究成果
The proposed intrarenal vessel segmentation algorithm and methodology for creating 3D patient-specific models are effective and reliable, as demonstrated by quantitative evaluation and real-life application in a PCNL procedure. The tool facilitates preoperative planning and reduces the risk of complications, with potential for use in other minimally invasive surgeries after further refinement.
研究不足
The manual segmentation used for validation is time-consuming and may have inaccuracies due to difficulties in delineating thin vessels in 2D cross-sections. The algorithm requires user input for point indication, and the study was conducted on a small sample size of ten images, limiting generalizability. Future work should include larger patient groups and inter-observer variability assessment.
1:Experimental Design and Method Selection:
The study involved developing and validating an algorithm for segmenting intrarenal vessels from uro-CT scans, using image registration and segmentation techniques.
2:Sample Selection and Data Sources:
Ten uro-CT images from patients with renal stones were used, with spatial resolutions ranging from
3:669-967 mm and slice thicknesses from 1-5 mm. List of Experimental Equipment and Materials:
CT scanner for imaging, software for image processing (e.g., for registration and segmentation algorithms).
4:Experimental Procedures and Operational Workflow:
Steps included image registration of different CT phases (native, arterial, venous, delayed), segmentation of structures (arteries, kidney, PCS) using methods like thresholding, Frangi filtration, and Locally Adaptive Region Growing, and construction of a 3D model for surgical planning.
5:Data Analysis Methods:
Evaluation using metrics such as accuracy, precision, specificity, sensitivity, Dice coefficient, and Hausdorff average distance, compared to manual segmentations.
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