研究目的
To report multimodal imaging in a case of idiopathic neuroretinitis and speculate about the pathophysiology in this disease.
研究成果
Multimodal imaging in this case of idiopathic neuroretinitis indicated involvement of the optic disc, entire retina, and choroid, suggesting it could be termed neurochorioretinitis. Visual acuity recovered to normal, but some choroidal changes persisted. Further research with larger cohorts is necessary to elucidate the pathogenesis.
研究不足
The study is limited to a single case report, which may not be generalizable. The effectiveness of the short-term antibiotic treatment was unclear. Future studies with larger sample sizes are needed for a better understanding of the pathogenesis.
1：Experimental Design and Method Selection:
A case report design was used to describe the clinical presentation and imaging findings of a single patient with idiopathic neuroretinitis. Multimodal imaging techniques were employed to assess ocular structures.
2：Sample Selection and Data Sources:
One 37-year-old female patient presenting with unilateral visual loss was selected based on clinical symptoms and examination findings.
3：List of Experimental Equipment and Materials:
Fundus camera (TRC-50DX, Topcon), swept-source optical coherence tomography (DRI OCT Triton, Topcon), fluorescein angiography (Heidelberg Retina Angiograph 2, Heidelberg Engineering), wide-field indocyanine green angiography (Optos California, Optos plc), visual field examination (Humphrey Field Analyzer, Carl Zeiss Meditec), and head magnetic resonance imaging were used.
4：Experimental Procedures and Operational Workflow:
Ophthalmic examinations were conducted, including visual acuity testing, slit-lamp examination, fundus photography, OCT scans, angiography procedures, and visual field testing. Blood tests for various antibodies were performed to rule out infectious causes.
5：Data Analysis Methods:
Imaging findings were qualitatively analyzed to describe morphological changes in the retina, choroid, and optic disc. No specific statistical analysis was mentioned.
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