研究目的
To propose a new fat suppression method for PRFS-based MR thermometry to obtain accurate variation of phase angle.
研究成果
The G-PRFS method is simple and effective, significantly reducing fat effects in PRFS-based MR thermometry, with experimental results showing accurate temperature mapping across different water-fat ratios, though it has limitations in extreme fat conditions and other disturbances.
研究不足
The method is expected to fail as the voxel fat-water ratio approaches 100%; it suffers from motion-induced errors and field drifts; temperature changes should be small to avoid phase angle exceeding 360°; there are disturbances from proton density temperature dependency and fat's minor temperature sensitivity.
1：Experimental Design and Method Selection:
The study uses a geometric model-based fat suppression method (G-PRFS) for MR thermometry, involving double scans at the same TE point to capture complex MR images and applying geometric relationships to remove fat effects.
2：Sample Selection and Data Sources:
Two phantoms with different water-to-fat ratios (40:60 and 60:40 by volume) are used, created from peanut-oil-in-gelatin dispersions.
3：List of Experimental Equipment and Materials:
A BASDA 1.5 T MR machine is used for imaging; phantoms are heated actively.
4：5 T MR machine is used for imaging; phantoms are heated actively. Experimental Procedures and Operational Workflow:
4. Experimental Procedures and Operational Workflow: Reference images are captured after MR machine stabilization; heating is applied, and images are acquired at 5-minute intervals. Complex signals are analyzed using geometric models to compute phase angle variations and temperature changes.
5：Data Analysis Methods:
Temperature maps are derived using Formula (5) based on phase variations; comparisons are made with conventional PRFS methods.
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