研究目的
To assess the application of fluorine-18-deoxyglucose positron emission tomography and gallium scan in diagnosing and evaluating adult-onset Still's disease.
研究成果
FDG PET/CT combined with gallium-67 scan can aid in diagnosing adult-onset Still's disease by ruling out malignancies like lymphoma. FDG PET/CT alone is useful for assessing disease distribution, activity, and treatment response, as demonstrated by complete remission in follow-up imaging.
研究不足
The study is limited to a single case, which may not be generalizable. No bone marrow biopsy was performed to confirm bone marrow involvement, and the diagnosis relied on clinical criteria and imaging without larger cohort validation.
1：Experimental Design and Method Selection:
A case report design was used, involving diagnostic imaging and laboratory tests to evaluate a patient with suspected adult-onset Still's disease. Methods included PET/CT scans, gallium-67 scans, and biopsy procedures.
2：Sample Selection and Data Sources:
The sample was a single 53-year-old female patient presenting with body pain, joint pain, skin rashes, and lymphadenopathies. Data were obtained from clinical examinations, imaging studies, and laboratory tests.
3：List of Experimental Equipment and Materials:
Equipment included a PET/CT scanner for FDG imaging, a gallium-67 scanner, and materials for biopsy and laboratory analysis.
4：Experimental Procedures and Operational Workflow:
The patient underwent chest CT, FDG PET/CT scan, lymph node biopsy, gallium-67 scan, and laboratory tests for antibodies and enzymes. Treatment with steroids and NSAIDs was administered, followed by a follow-up PET/CT scan after six months.
5：Data Analysis Methods:
Data were analyzed qualitatively for imaging findings (e.g., FDG uptake patterns) and quantitatively for laboratory values (e.g., alanine aminotransferase levels). Standard uptake values from PET/CT were compared pre- and post-treatment.
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