研究目的
To discuss the potential extension of coronary artery calcium (CAC) scanning from screening asymptomatic populations to clinical applications in symptomatic or asymptomatic patients being evaluated for obstructive coronary artery disease (CAD), particularly in combination with myocardial perfusion imaging (MPI).
研究成果
The evidence suggests that CAC scanning can aid in better patient selection for MPI, improve diagnostic interpretation, enhance prognostic assessment, and lead to greater changes in therapy. While not yet proven for routine combination, it merits further study and consideration in clinical practice.
研究不足
The paper highlights limitations such as the paucity of large studies on the relationship between CAC scores and myocardial ischemia, variability in ischemia frequency across studies due to clinical and technical factors, and the need for standardized interpretation criteria and further research to optimize clinical use.
