研究目的
To present an overview of commonly used synthetic methods and to highlight recent developments in the synthesis and modification of BODIPY dyes.
研究成果
Considerable work has been directed toward the development and optimization of synthetic routes to functionalized BODIPY architectures. Recent developments include direct CdH functionalization, radical-mediated functionalization, and other innovative methods, but there are still unsolved synthetic problems, such as functionalization at the 1,7-positions, indicating ongoing research opportunities.
研究不足
The review does not provide a comprehensive review of the literature but highlights modern and improved synthetic methods through representative selected examples. It focuses on the last 10 years and may not cover all aspects or recent advancements beyond the publication date.
1：Experimental Design and Method Selection:
The paper is a review, so it does not describe a specific experimental design but summarizes various synthetic methods for BODIPY dyes, including condensation reactions, boron chelation, electrophilic and nucleophilic substitutions, cross-coupling reactions, and other functionalization strategies.
2：Sample Selection and Data Sources:
The review compiles examples from the literature, citing numerous references.
3：List of Experimental Equipment and Materials:
Not specified as it is a review.
4：Experimental Procedures and Operational Workflow:
Describes step-by-step procedures for different synthetic routes, e.g., condensation of pyrroles with acid anhydrides, chlorides, orthoesters, thiophosgenes, aldehydes, followed by oxidation and boron chelation.
5：Data Analysis Methods:
Not applicable as it is a review.
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