研究目的
To provide an overview of molecular theranostic agents designed for potential applications in magnetic resonance imaging (MRI) and photodynamic therapy (PDT).
研究成果
Molecular theranostic agents for MRI and PDT show superior imaging properties and potential for treatment optimization due to increased relaxivity, cellular uptake, and tumor accumulation. However, further studies are needed to improve tumoral selectivity, stability, and to optimize treatment parameters for clinical application.
研究不足
The paper is a review and does not conduct new experiments; limitations include the complexity and time-consuming synthesis of molecular theranostic agents, stability issues in some cases, and the need for optimization of parameters such as drug dose and light application for effective PDT. Clinical translation remains challenging.
This is a review paper; it does not describe a specific experimental scheme. It summarizes and discusses existing studies on molecular theranostic agents combining MRI contrast agents and PDT photosensitizers, including their design, synthesis, properties (e.g., relaxivity, absorption characteristics), and in vitro and in vivo evaluations.
独家科研数据包，助您复现前沿成果，加速创新突破
获取完整内容-
Photofrin
Photosensitizer for photodynamic therapy
-
Visudyne
Photosensitizer for photodynamic therapy
-
Tookad
WST11
Photosensitizer for photodynamic therapy
-
LUZ11
Photosensitizer for photodynamic therapy
-
Dotarem
MRI contrast agent
-
Clariscan
MRI contrast agent
-
Magnevist
MRI contrast agent
-
GdDOTA
MRI contrast agent
-
GdDTPA
MRI contrast agent
-
HPPH-3GdDTPA
Theranostic agent for MRI and PDT
-
ZnPht-1Gd
Theranostic agent for MRI and PDT
-
ZnPz-nGd
n=1,4,8
Theranostic agent for MRI and PDT
-
GdPz1
Theranostic agent for MRI and PDT
-
GdPz2
Theranostic agent for MRI and PDT
-
Gd/Pt-P1
Theranostic agent for MRI, PDT, and chemotherapy
-
DPP-ZnP-GdDOTA
Theranostic agent for MRI and PDT with one- and two-photon activation
-
ZnP–ZnP-GdDOTA
Theranostic agent for MRI and PDT with one- and two-photon activation
-
登录查看剩余15件设备及参数对照表
查看全部
