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A facile dopamine-assisted method for the preparation of antibacterial surfaces based on Ag/TiO2 nanoparticles
摘要： Highly effective antibacterial surfaces are crucial to prevent bacterial infections. In this work, we developed a simple method based on Ag/TiO2 nanoparticles via a dopamine-assisted process with long-term antibacterial efficacy, for the preparation of antibacterial glass surfaces. The chemical and morphological features of the prepared surfaces were investigated through field-emission scanning electron microscopy coupled with energy-dispersive X-ray spectrometry, X-ray diffraction, and X-ray photoelectron spectrometry. The ultraviolet-visible spectroscopy absorption spectra of the prepared glass samples were measured with a spectrophotometer. The prepared Ag/TiO2 nanoparticle modified surfaces exhibited high activity in the elimination of the Gram-negative Escherichia coli and Gram-positive Bacillus subtilis bacteria under visible light and still maintained good antibacterial properties against E. coli after immersion in phosphate buffered saline solution for 60 days.
关键词： Silver,Dopamine,Titanium dioxide,Glass,Antibacterial property
更新于2025-11-21 11:08:12
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Surface functionalization of titanium with zinc/strontium-doped titanium dioxide microporous coating via microarc oxidation
摘要： Deficient osseointegration and implant-related infections are pivotal issues for the long-term clinical success of titanium (Ti) implants. Zinc (Zn) and strontium (Sr) serve dual functions by promoting osteogenesis and inhibiting bone destruction, and Zn has good antibacterial activity. As such, this study examined the preparation of a Zn/Sr-doped titanium dioxide microporous coating (MT-Zn/Sr) on a Ti surface using microarc oxidation (MAO), with Zn and Sr evenly distributed throughout the coating. In vitro, the coating could promote the adhesion, proliferation, differentiation and mineralization of osteoblasts, showing good biological activity. Antibacterial testing demonstrated the good antibacterial activity of the coating, as it inhibited the proliferation of Staphylococcus. In vivo, MT-Zn/Sr promoted early osseointegration between the Ti substrate and the bone tissue. This work is expected to provide a new method for improving the biological activity of Ti implants and thus has important theoretical significance and great clinical prospects.
关键词： Osseointegration,Strontium,Zinc,Titanium coating,Antibacterial property
更新于2025-09-23 15:23:52
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The antibacterial effect of potassium-sodium niobate ceramics based on controlling piezoelectric properties
摘要： The implant infection is one of the most serious postsurgical complications of medical device implantation. Therefore, the development of biocompatible materials with improved antibacterial properties is of great importance. It might be a new insight to apply the intrinsic electrical properties of biomaterials to solve this problem. Here, potassium-sodium niobate piezoceramics (K0.5Na0.5NbO3, KNN) with different piezoelectric constants were prepared, and the microstructures and piezoelectric properties of these piezoceramics were evaluated. Moreover, the antibacterial effect and biocompatibility of these piezoceramics were assayed. Results showed that these piezoceramics were able to decrease the colonies of bacteria staphylococcus aureus (S. aureus), favor the rat bone marrow mesenchymal stem cells (rBMSCs) proliferation and promote the cell adhesion and spreading. The above effects were found closely related to the surface positive charges of the piezoceramics, and the sample bearing the most positive charges on its surface (sample 80KNN) had the best performance in both antibacterial effect and biocompatibility. Based on our work, it is feasible to develop biocompatible antibacterial materials by controlling piezoelectric properties.
关键词： Positive charges,Biocompatibility,Potassium-sodium niobate,Antibacterial property
更新于2025-09-23 15:19:57