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[IEEE 2018 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) - Honolulu, HI, USA (2018.7.18-2018.7.21)] 2018 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) - Towards an ASIC-based Fluoroscopic Capsule for the Early Cancer Detection in the Small Intestine
摘要: Early micro-cancer detection in the small intestine can be realized using infrared fluorescence endoscopy (IRFE) in conjunction with an infrared fluorescence biomarker. In this paper, we present a third-generation capsule that detects weak fluorescence signals emitted by low concentrations of indocyanine green (ICG). An application-specific integrated circuit (ASIC) has been designed and fabricated that integrates many of the peripheral components of the capsule system. The ASIC enables the system to have greater sensitivity whilst reducing the capsule size and lowering the power consumption.
关键词: infrared fluorescence endoscopy,small intestine,indocyanine green,application-specific integrated circuit,early cancer detection
更新于2025-09-10 09:29:36
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D <sup>2</sup> R <sub/>1</sub> : A 2-D X-Ray Detector for CdTe-Based Fine Pitch and High-Energy Resolution Imaging Spectroscopy
摘要: This paper describes a 16 × 16 pixels CdTe-based X-ray detector named dimension 2 revision 1 (D2R1) with a pixel size of 300 μm× 300 μm. An application-specific integrated circuit (ASIC) is interconnected to a CdTe detector by means of an indium gold stud bonding process. This ASIC has a mean equivalent noise charge of 29 el.rms (at 0 pF). The combination of a low capacitance interconnection and low-dark-current detector (0.5 pA) with an optimized ASIC results in a spectral resolution of 584-eV full-width at half-maximum at 60 keV, an energy threshold of 2 keV with a dynamic range of 250 keV. A filtering stage made of a multicorrelated double sampling allows the system to measure X-ray photons at a frequency of 10 kcounts/s typically suited for low photon flux less than 3000 photons · cm?2·s?1. The energy range, resolution, and timing capability of D2R1 can suite a variety of different applications such as X-ray astrophysics, nuclear safety, or medical applications.
关键词: Application-specific integrated circuits (ASICs),electronics,spectroscopy,energy resolution,X-rays,CdTe,low-noise,imaging
更新于2025-09-10 09:29:36
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Plasmon-enhanced upconversion photoluminescence: mechanism and application
摘要: The enhanced local electromagnetic field (EM) excited on the noble metallic nanostructure exhibits potential application in various areas, particularly in surface-enhanced spectroscopy (SES). Resonant coupling of SPs to luminous centers can strongly moderate the emission spectra properties, including the angular distribution, the intensity, the speed of radiative decay, and even the spectrum radiation polarization, or so-called plasmon-enhanced fluorescence (PEF). Due to the low efficiency of emission and small absorption section of rare earth ions, plasmon-enhanced upconversion photoluminescence(PUCPL) has attracted increasing attention recently. In this review, we focus on recent advanced reports on PUCPL. First, the mechanism of the conventional upconversion process and related reports will be introduced. We will then demonstrate that the introduction of plasmonic nanostructure, including nonperiodic and periodic metallic nanostructures, has a critical effect on upconversion nanoparticles(UCNPs). The recent advances in plasmon-enhanced fluorescence with metallic tip configuration are also noted. Finally, the recent applications of PUCPL are introduced. As a result, the combination of a rare-earth luminescent center with plasmonic nanostructure can largely expand the application of upconversion materials.
关键词: surface-enhanced spectroscopy,mechanism,plasmonic nanostructure,Plasmon-enhanced upconversion photoluminescence,application,rare earth ions
更新于2025-09-10 09:29:36
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[Nanostructure Science and Technology] Nanowire Electronics || Properties Engineering of III–V Nanowires for Electronic Application
摘要: Semiconductors have been the core materials of many technological advances in recent years. Silicon, the most studied and used semiconducting material, has been the center of semiconductor industry for decades because it is available abundantly and easy to dope, and silicon dioxide is a superior dielectric material in microelectronic industry. This material can be used to make computer chips, optoelectronics devices, and solar cell. Silicon reshapes the way we live and is unarguably one of the most important materials in modern society. Through its dominant role in the semiconductor industry for now, the search for alternatives is fueled by the unstoppable demand for high-performance and low-power electronics. Among different kinds of semiconductors, III–V semiconductor holds promising properties for replacing silicon, and in particular, the NW structure of III–V semiconductor has been studied extensively.
关键词: nanowire field-effect transistor,semiconductors,contact engineering,crystal engineering,III–V nanowires,surface modification,electronic application
更新于2025-09-09 09:28:46
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Recent progress in synthesis, properties and applications of hexagonal boron nitride based heterostructures
摘要: Featuring an absence of dangling bonds, large band gap, low dielectric constant, excellent chemical inertness, atomically thin hexagonal boron nitride (h-BN) is considered as an ideal candidate for the integration with graphene and other 2D materials. During the past years, great efforts have been devoted to the research area of h-BN based heterostructures from fundamental study to practical applications. In this review, we summarize the recent progress in the synthesis, novel properties and potential applications of h-BN based heterostructures, especially the synthesis technique. Firstly, various approaches for the preparation of both in-plane and vertical stacked h-BN based heterostructures are introduced in detail, including top-down strategies associated with exfoliation-transfer processes and bottom-up strategies such as chemical vapor deposition (CVD)-based growth. Secondly, we discuss some novel properties arise in these heterostructures. Then, several promising applications in electronic and optoelectronic devices based on these heterostructures are also reviewed. Finally, we discuss the main challenges and possible research directions in this field.
关键词: heterostructures,application,hexagonal boron nitride,property,synthesis
更新于2025-09-09 09:28:46
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[IEEE 2018 4th International Conference on Computer and Information Sciences (ICCOINS) - Kuala Lumpur (2018.8.13-2018.8.14)] 2018 4th International Conference on Computer and Information Sciences (ICCOINS) - Designing Page Scrolling Gesture using Gesture-Specific Heuristics in Leap Motion Validating The Gesture-Specific Heuristics By Creating Optimal Gestures
摘要: Optimal gesture creation is marred with many uncertainties, challenges and is still at its infancy stage. For hand-tracking devices such as that invented by Leap Motion, there is a lack of well-established gestures on controlling the operating system to perform basic operations. The gesture-specific heuristics (GSH) are a set of guidelines that could be used to evaluate and design gestures that would suit the limitation of the device and operating environment. This study narrows the gesture design to a single activity – simulating mouse wheel scrolling. However, the designing process comes with major obstacles. GSH needs to be supplemented with existing usability heuristics that tackles non-gestural design issues. The end results of combining GSH with existing usability heuristics produces a gesture that is more optimal than the existing available solutions. Moving forward, additional heuristics, taking into account user expectancy of the gesture nature needs to be considered.
关键词: mobile application,usability model,gesture interaction,gesture design
更新于2025-09-09 09:28:46
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Non-Invasive Diagnosis of Diabetes by Volatile Organic Compounds in Urine Using FAIMS and Fox4000 Electronic Nose
摘要: The electronic nose (eNose) is an instrument designed to mimic the human olfactory system. Usage of eNose in medical applications is more popular than ever, due to its low costs and non-invasive nature. The eNose sniffs the gases and vapours that emanate from human waste (urine, breath, and stool) for the diagnosis of variety of diseases. Diabetes mellitus type 2 (DM2) affects 8.3% of adults in the world, with 43% being underdiagnosed, resulting in 4.9 million deaths per year. In this study, we investigated the potential of urinary volatile organic compounds (VOCs) as novel non-invasive diagnostic biomarker for diabetes. In addition, we investigated the influence of sample age on the diagnostic accuracy of urinary VOCs. We analysed 140 urine samples (73 DM2, 67 healthy) with Field-Asymmetric Ion Mobility Spectrometry (FAIMS); a type of eNose; and FOX 4000 (AlphaM.O.S, Toulouse, France). Urine samples were collected at UHCW NHS Trust clinics over 4 years and stored at ?80 ?C within two hours of collection. Four different classifiers were used for classification, specifically Sparse Logistic Regression, Random Forest, Gaussian Process, and Support Vector on both FAIMS and FOX4000. Both eNoses showed their capability of diagnosing DM2 from controls and the effect of sample age on the discrimination. FAIMS samples were analysed for all samples aged 0–4 years (AUC: 88%, sensitivity: 87%, specificity: 82%) and then sub group samples aged less than a year (AUC (Area Under the Curve): 94%, Sensitivity: 92%, specificity: 100%). FOX4000 samples were analysed for all samples aged 0–4 years (AUC: 85%, sensitivity: 77%, specificity: 85%) and a sub group samples aged less than 18 months: (AUC: 94%, sensitivity: 90%, specificity: 89%). We demonstrated that FAIMS and FOX 4000 eNoses can discriminate DM2 from controls using urinary VOCs. In addition, we showed that urine sample age affects discriminative accuracy.
关键词: biosensor,urine sample,medical application,electronic nose,non-invasive diagnosis,FOX 4000,volatile organic compounds (VOCs),FAIMS,diabetes
更新于2025-09-09 09:28:46
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[IEEE 2018 IEEE International Conference on RFID Technology & Application (RFID-TA) - Macau, Macao (2018.9.26-2018.9.28)] 2018 IEEE International Conference on RFID Technology & Application (RFID-TA) - Low-power and Compact Microwave RFID Reader for Sensing Applications in Space
摘要: Radio frequency identi?cation (RFID) is the driving technology behind many compelling applications, such as internet-of-things (IoT), smart cities, and particle tracking. However, it is always challenging to make small, low-cost transponder with little power consumption. RFID tags are useful for a host of distributed sensing applications because they do not require a wired power source and use very little power to communicate wirelessly. Such tags also have great potential for use in sensing applications onboard spacecraft including spacecraft structural health monitoring and sensitive ?eld measurements. This paper proposed the design and characterization process of a low-power, compact RFID transceiver for sensing applications in space. This reader operates at the 5725-5850 MHz frequency ISM band with 31 dBm equivalent isotropically radiated power (EIRP) and -58 dBm to -82 dBm sensitivity in different conditions.
关键词: Space Application,RFID reader,Antennas
更新于2025-09-09 09:28:46
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[ACM Press the 33rd Annual ACM Symposium - Pau, France (2018.04.09-2018.04.13)] Proceedings of the 33rd Annual ACM Symposium on Applied Computing - SAC '18 - A smartphone application to measure the quality of pest control spraying machines via image analysis
摘要: The need for higher agricultural productivity has demanded the intensive use of pesticides. However, their correct use depends on assessment methods that can accurately predict how well the pesticides’ spraying covered the intended crop region. Some methods have been proposed in the literature, but their high cost and low portability harm their widespread use. This paper proposes and experimentally evaluates a new methodology based on the use of a smartphone-based mobile application, named DropLeaf. Experiments performed using DropLeaf showed that, in addition to its versatility, it can predict with high accuracy the pesticide spraying. DropLeaf is a five-fold image-processing methodology based on: (i) color space conversion; (ii) threshold noise removal; (iii) convolutional operations of dilation and erosion; (iv) detection of contour markers in the water-sensitive card; and, (v) identification of droplets via the marker-controlled watershed transformation. The authors performed successful experiments over two case studies, the first using a set of synthetic cards and the second using a real-world crop. The proposed tool can be broadly used by farmers equipped with conventional mobile phones, improving the use of pesticides with health, environmental and financial benefits.
关键词: Image Processing,Deposition Analysis,Pesticide Spraying Analysis,Mobile Application
更新于2025-09-09 09:28:46
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A Biomedical Surface Enhanced Raman Scattering Substrate: Functionalized Three-Dimensional Porous Membrane Decorated with Silver Nanoparticles
摘要: We fabricated a simple, cheap, and functional surface enhanced Raman scattering substrate for biomedical application. Hotspots between two close silver nanoparticles distributed in the skeleton of a three-dimensional porous membrane, especially in the pores, were formed. The dual poles of micropores in the membrane were discussed. The pores could protect the silver nanoparticles in the pores from being oxidized, which makes the membrane effective for a longer period of time. In addition, Staphylococcus aureus cells could be trapped by the micropores and then the Raman signal became stronger, indicating that the functional surface enhanced Raman scattering substrate is reliable.
关键词: three-dimensional porous membrane,biomedical application,silver nanoparticles,surface enhanced Raman scattering
更新于2025-09-09 09:28:46