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The first deaf-blind patient in Russia with Argus II retinal prosthesis system. What he sees and why
摘要： A 59-year-old man with retinitis pigmentosa and hearing loss (clinical Usher syndrome) underwent surgery to implant the Argus II retinal prosthesis system in the right eye. This is the first case of retinal implant surgery in the Russian Federation. In this study we propose a new method for evaluating the functional results after implantation of the Argus II, the statistical analysis was performed to find correlations between the sizes of phosphenes that the patient drew and then were digitalized, and the height of the subimplant interface, retinal thickness, impedance, and perceptual threshold, which showed interesting mixed results. Correlation analysis showed the weak dependency between the size of a phosphene and the perceptual threshold and we did not find significant correlations between a phosphene and the height of the interface, impedance and retinal thickness.
关键词： Argus II,Usher syndrome,retinitis pigmentosa,deaf-blind,blind,artificial vision,retinal prosthesis system,retinal implant,deafblind
更新于2025-09-23 15:23:52
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Argus II retinal prosthesis malrotation and repositioning with intraoperative optical coherence tomography in a posterior staphyloma
摘要： The Argus II retinal prosthesis may improve visual function in patients with severe vision loss from retinitis pigmentosa. Optimal centration of the electrode array over the macula is important to achieve optimal visual results. Argus tack malrotation is a novel entity that may be encountered during placement, especially in patients with posterior staphyloma. Methods: Retrospective case review. Results: During tacking of the electronics array a clockwise rotation occurred resulting in malposition. We hypothesize this was secondary to undue rotation or posterior pressure applied during tack insertion in conjunction with placement over a previously unrecognized posterior staphyloma. Intraoperative optical coherence tomography, because of the cross-sectional images provided, was helpful in visualizing the distance between the electronics array and the retina, which was difficult to assess using the surgical microscope alone. Repositioning was achieved by adjusting the tack without removal. The patient experienced an improvement in vision as a result of the surgery. Conclusion: Malrotation may occur when tacking the Argus II prosthesis, and the presence of a posterior staphyloma may increase this risk. It is important to differentiate malrotation from tack misplacement – the former may be addressed with array unrotation or partial tack withdrawal and the latter may require tack removal and reinsertion. Also, intraoperative optical coherence tomography may be helpful in characterizing electronics array position during surgery.
关键词： retinal tack,retinitis pigmentosa,Argus
更新于2025-09-09 09:28:46
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Remote Sensing Is Changing Our View of the Coast: Insights from 40 Years of Monitoring at Narrabeen-Collaroy, Australia
摘要： Narrabeen-Collaroy Beach, located on the Northern Beaches of Sydney along the Pacific coast of southeast Australia, is one of the longest continuously monitored beaches in the world. This paper provides an overview of the evolution and international scientific impact of this long-term beach monitoring program, from its humble beginnings over 40 years ago using the rod and tape measure Emery field survey method; to today, where the application of remote sensing data collection including drones, satellites and crowd-sourced smartphone images, are now core aspects of this continuing and much expanded monitoring effort. Commenced in 1976, surveying at this beach for the first 30 years focused on in-situ methods, whereby the growing database of monthly beach profile surveys informed the coastal science community about fundamental processes such as beach state evolution and the role of cross-shore and alongshore sediment transport in embayment morphodynamics. In the mid-2000s, continuous (hourly) video-based monitoring was the first application of routine remote sensing at the site, providing much greater spatial and temporal resolution over the traditional monthly surveys. This implementation of video as the first of a now rapidly expanding range of remote sensing tools and techniques also facilitated much wider access by the international research community to the continuing data collection program at Narrabeen-Collaroy. In the past decade the video-based data streams have formed the basis of deeper understanding into storm to multi-year response of the shoreline to changing wave conditions and also contributed to progress in the understanding of estuary entrance dynamics. More recently, ‘opportunistic’ remote sensing platforms such as surf cameras and smartphones have also been used for image-based shoreline data collection. Commencing in 2011, a significant new focus for the Narrabeen-Collaroy monitoring program shifted to include airborne lidar (and later Unmanned Aerial Vehicles (UAVs)), in an enhanced effort to quantify the morphological impacts of individual storm events, understand key drivers of erosion, and the placing of these observations within their broader regional context. A fixed continuous scanning lidar installed in 2014 again improved the spatial and temporal resolution of the remote-sensed data collection, providing new insight into swash dynamics and the often-overlooked processes of post-storm beach recovery. The use of satellite data that is now readily available to all coastal researchers via Google Earth Engine continues to expand the routine data collection program and provide key insight into multi-decadal shoreline variability. As new and expanding remote sensing technologies continue to emerge, a key lesson from the long-term monitoring at Narrabeen-Collaroy is the importance of a regular re-evaluation of what data is most needed to progress the science.
关键词： Argus,CoastSnap,Google Earth Engine,surfcams,Unmanned Aerial Vehicle,coastal imaging,lidar,RTK-GPS surveys
更新于2025-09-04 15:30:14
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ADVERSE EVENTS OF THE ARGUS II RETINAL PROSTHESIS
摘要： To analyze and provide an overview of the incidence, management, and prevention of conjunctival erosion in Argus II clinical trial subjects and postapproval patients. This retrospective analysis followed the results of 274 patients treated with the Argus II Retinal Prosthesis System between June 2007 and November 2017, including 30 subjects from the US and European clinical trials, and 244 patients in the postapproval phase. Results were gathered for incidence of a serious adverse event, incidence of conjunctival erosion, occurrence sites, rates of erosion, and erosion timing. Overall, 60% of subjects in the clinical trial subjects versus 83% of patients in the postapproval phase did not experience device- or surgery-related serious adverse events. In the postapproval phase, conjunctival erosion had an incidence rate of 6.2% over 5 years and 11 months. In 55% of conjunctival erosion cases, erosion occurred in the inferotemporal quadrant, 25% in the superotemporal quadrant, and 20% in both. Sixty percent of the erosion events occurred in the first 15 months after implantation, and 85% within the first 2.5 years. Reducing occurrence of conjunctival erosion in patients with the Argus II Retinal Prosthesis requires identification and minimization of risk factors before and during implantation. Implementing inverted sutures at the implant tabs, use of graft material at these locations as well as Mersilene rather than nylon sutures, and accurate Tenon’s and conjunctiva closure are recommended for consideration in all patients.
关键词： conjunctival erosion,retinitis pigmentosa,retinal prosthesis,Argus II,epiretinal implant
更新于2025-09-04 15:30:14