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Skin and subcutaneous fat morphology alterations under the LED or laser treatment in rats in vivo
摘要： The main objective of this work is to quantify the dynamic/photothermal treatment by using visible LED and NIR laser irradiation through the skin of subcutaneous fat in vivo followed up by tissue sampling and histology. The optical method may provide reduction of regional or site-specific accumulations of abdominal or subcutaneous adipose tissue precisely and least-invasively by inducing cell apoptosis and controlled necrosis of fat tissue. As photo-dynamic/photothermal adipose tissue sensitizers Brilliant Green (BG) or Indocyanine Green (ICG) dyes were injected subcutaneously in rats. The CW LED device (625 nm) or CW diode laser (808 nm) were used as light sources, respectively. Biopsies of skin together with subcutaneous tissues were taken for histology. The combined action BG-staining and LED-irradiation (BG + LED) or ICG-staining and NIR-laser irradiation (ICG + NIR) causes pronounced signs of damage of adipose tissue characterized by a strong stretching, thinning, folding and undulating of cell membranes and appearance of necrotic areas. As a posttreatment after 14 days only connective tissue was observed at the site of necrotic areas. The data obtained are important for safe light treatment of site-specific fat accumulations, including cellulite. This work provides a basis for the development of fat lipolysis technologies and to move them to clinical applications.
关键词： visible light,laser,optical microscopy,fat morphology,skin,subcutaneous adipose tissue,photodynamic and photothermal treatment,LED,Brilliant Green,NIR,Indocyanine Green (ICG)
更新于2025-09-11 14:15:04
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N-S Codoped Cerium-Cobalt Oxide Bimetal Nanoparticles Catalyzed Photodegradation of Brilliant Green and Fast Green
摘要： Cerium-cobalt oxide bimetal nanoparticles were synthesized using wet precipitation method and characterized by X-ray diffraction (XRD) and scanning electron microscopy (SEM). The photocatalyzed degradation of brilliant green and fast green dyes were studied using CeCoO3 bimetallic nanoparticles spectrophotometrically. Photocatalytic activity has been tested in the reaction of these dyes under visible irradiation. It was revealed that doping enhanced the photocatalytic activity at low doping levels but reduced the activity at high doping levels. Various parameters like amount of semiconductor, pH, light intensity, dye concentration, % of dopant were also studied. The rate of reaction followed pseudo-first order kinetics.
关键词： Nanoparticles,Fast green,Brilliant green,Cerium-Cobalt oxide,Photodegradation
更新于2025-09-09 09:28:46
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Preparation of C60 Nanowhiskers/NiS2 Nanocomposites and Photocatalytic Degradation of Organic Dyes
摘要： [C60]Fullerene nanowhiskers/NiS2 nanocomposites were prepared by a reaction of NiS2 nanoparticles and C60 nanowhiskers. The C60 nanowhiskers (FNWs) were synthesized by a liquid-liquid interfacial precipitation method using solvent solutions, such as benzene and toluene saturated with C60 powder and isopropyl alcohol. The NiS2 nanoparticles were synthesized by a reaction of NiCl2·H2O and Na2S2O3·5H2O in deionized water under microwave irradiation. The C60 nanowhiskers/NiS2 nanocomposites were calcined in an electric furnace at 700 °C for 2 h. The C60 nanowhiskers/NiS2 nanocomposites were characterized by X-ray diffraction and UV-visible spectrophotometry. The C60 nanowhiskers/NiS2 nanocomposites were evaluated as a photocatalyst by UV-visible spectrophotometry in the degradation of organic dyes, such as methylene blue and brilliant green, under ultraviolet light at 365 nm.
关键词： [C60]Fullerene nanowhiskers,Brilliant green,NiS2 nanoparticles,Photocatalytic degradation,Methylene blue
更新于2025-09-04 15:30:14