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Relationship between body habitus and image quality and radiation dose in chest X-ray examinations: A phantom study
摘要： Purpose: To evaluate the influence of being overweight on image quality (IQ), radiation dose and acquisition parameters when undertaking adult chest X-ray (CXR) examinations using routine acquisition protocols. Methods: The Lungman chest phantom, with and without chest plates, was used to simulate the chest region for larger size and average adult patients, respectively. Radiographic acquisitions were conducted using 17 X-ray machines located in eight hospitals using their routine clinical protocols. IQ was assessed using relative visual grading analysis (VGA) and 2 alternative forced choice (2AFC) by six observers. Incident air kerma (IAK) was measured using a solid-state dosimeter. Results: IQ mean (range) scores between the hospitals were 16.2 (12.0–21.3) with a 56.0% difference and 20.9 (14.1–23.6) with a 50.2% difference for the standard and larger size phantoms, respectively. IAK mean (range) scores 63 μGy (19–136 μGy) with a 150% difference and 159 μGy (27–384 μGy) with a 173% difference for the standard and larger size phantoms, respectively. The chest plates had a significant negative impact on IQ (P = 0.001) and lead to an increased in IAK by approximately 50%. Conclusion: Visual measures of IQ and IAK showed large differences between hospitals for standard and larger phantom sizes; differences within the hospitals was lower. Overall, Lungman with chest plates was found to degrade IQ and increase radiation dose by a factor of two. Further optimisation is required especially for the larger sized patient’s imaging protocols for all eight hospitals.
关键词： Overweight,Image quality,Obesity,Adult chest radiography,Dose optimisation,Radiation dose
更新于2025-09-23 15:23:52
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Shaping of a laser-accelerated proton beam for radiobiology applications via genetic algorithm
摘要： Laser-accelerated protons have a great potential for innovative experiments in radiation biology due to the sub-picosecond pulse duration and high dose rate achievable. However, the broad angular divergence makes them not optimal for applications with stringent requirements on dose homogeneity and total flux at the irradiated target. The strategy otherwise adopted to increase the homogeneity is to increase the distance between the source and the irradiation plane or to spread the beam with flat scattering systems or through the transport system itself. Such methods considerably reduce the proton flux and are not optimal for laser-accelerated protons. In this paper we demonstrate the use of a Genetic Algorithm (GA) to design an optimal non-flat scattering system to shape the beam and efficiently flatten the transversal dose distribution at the irradiated target. The system is placed in the magnetic transport system to take advantage of the presence of chromatic focusing elements to further mix the proton trajectories. The effect of a flat scattering system placed after the transport system is also presented for comparison. The general structure of the GA and its application to the shaping of a laser-accelerated proton beam are presented, as well as its application to the optimisation of dose distribution in a water target in air.
关键词： Genetic algorithm,Beam shaping,Laser-driven protons,Monte Carlo simulations,Dose optimisation
更新于2025-09-16 10:30:52