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Re: Erbium:YAG Laser Treatment of Female Stress Urinary Incontinence: Midterm Data
摘要： The role of intravaginal laser therapy for the treatment of women with a clinical and urodynamic diagnosis of stress urinary incontinence (SUI) or mixed urinary incontinence was the focus of the recent study by Kuszka and colleagues. To evaluate subjective and objective outcomes of Er:YAG therapy with SMOOTH mode technology, the authors enrolled 59 women, of whom 32 had grade I (54%), 16 had grade II (27%), and 11 had grade III SUI (19%). Using validated questionnaires (ICIQ-UI SF, PISQ 12) and 1-h pad weight at baseline, after two, four, and five laser sessions, and at 6-mo and 2-yr follow-up, the authors found that intravaginal laser therapy led to cure/improvement for grades I and II but not for severe SUI. At least three laser sessions at intervals of 1 mo are required to obtain better results from laser therapy. Outcomes at the 6-mo and 2-yr follow-up visits were similar, indicating that laser treatment is suitable and does not need to be repeated within 2 yr.
关键词： Female Stress,Urinary Incontinence,Midterm Data,Treatment,Erbium:YAG Laser
更新于2025-09-19 17:13:59
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Treatment of Congenital Melanocytic Nevi in the Eyelid and Periorbital Region With Ablative Lasers
摘要： Background: Congenital melanocytic nevi (CMN) that occur on the eyelid and periorbital region cause cosmetic disfiguring. Laser treatment has aroused interest as an alternative treatment method, and resurfacing lasers have shown promising results. Objective: This study aimed to evaluate the efficacy and safety of carbon dioxide laser and erbium:yttrium aluminum garnet laser to treat CMN of the eyelid and periorbital region. Methods and Materials: Twenty patients with CMN were included in this study and were treated with either the CO2 or erbium:yttrium aluminum garnet laser. Clinical efficacy outcomes were evaluated by visual assessment and L*a*b* color space evaluation at least 6 months after treatment. Results: The average (SD) visual evaluation improvement, assessed on a 5-point scale, was 2.8 (1.27). The mean (SD) values of the relative L* improvement rate and blanching rate of the CMN lesion were 32.0% (47.9%) and 34.1% (36.2%), respectively. Spearman rank correlation coefficient between the objective and subjective evaluations was significant (P < 0.001). Three cases developed partial hypopigmentation. No patient developed hypertrophic scars. Conclusion: The outcomes after laser treatment were variable, although half of the patients achieved greater than 50% clearance. It provides an alternative to surgical excision for the removal of CMN in the difficult regions. Surgery excision is inevitable for some patients.
关键词： carbon dioxide laser,eyelid and periorbital region,congenital melanocytic nevi,ablative laser,Erbium:YAG laser
更新于2025-09-12 10:27:22
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Erbium:YAG laser treatment of female stress urinary incontinence: midterm data
摘要： Introduction and hypothesis Stress urinary incontinence (SUI) is treated using intravaginal laser therapy. We wanted to find out how incontinence severity at baseline and the number of laser interventions affect success rate, and whether the effect of laser therapy was obvious 6 months and 2 years after the last laser intervention. Methods Fifty-nine women, 32 with SUI I, 16 with SUI II, and 11 with SUI III were treated using an erbium-doped yttrium aluminium garnet (Er:YAG) laser following the IncontiLase? protocol. Therapy included five laser sessions with a 1-month interval between sessions. Objective (1-h pad test) and subjective data (International Consultation on Incontinence Questionnaire-Urinary Incontinence Short Form [ICIQ-UI SF], Pelvic Organ Prolapse/Urinary Incontinence Sexual Questionnaire [PISQ-12]) were assessed at baseline, after two and four laser sessions and 6 months and 2 years after the fifth laser session. Results Objective cure/improve rates for mild SUI I were 69%, 78%, 91%, and 78% after two, four, and five laser sessions at the 6-month and 2-year follow-ups. Subjective cure rates (ICIQ-UI SF) were 53%, 69%, 72%, and 66%, and sexual function (PISQ-12) also improved. For SUI II, objective cure/improve rates were 31%, 63%, 69%, and 50%. Subjective cure rate was 13% at the 2-year follow-up. For SUI III, only one patient had an objective improvement after two and four laser sessions. Conclusions Intravaginal laser therapy led to cure/improvement for SUI I and SUI II, but not for severe SUI III. Outcome was better after four to five laser sessions than after two laser sessions. Follow-up data 6 months and 2 years after laser intervention showed sustainability of the treatment.
关键词： ICIQ-UI SF,1-h pad test,Stress urinary incontinence,Intravaginal laser therapy,Erbium:YAG laser,Non-ablative SMOOTH mode
更新于2025-09-12 10:27:22