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Application of 180W XPS GreenLight laser vaporization of the prostate for treatment of benign prostatic hyperplasia
摘要： Purpose: To evaluate safety, ef?cacy and clinical outcomes after photovaporization of the prostate with the 180W-XPS Greenlight laser in patients with low urinary tracts symptom secondary to benign prostatic hyperplasia (BPH). Materials and Methods: All 102 patients with lower urinary tract symptoms who underwent 180W XPS laser vaporization of the prostate from April 2017 to April 2018 were enrolled. The preoperative parameters, postoperative functional, uro?owmetry outcomes and complications were collected. Results: All patients were successfully treated with 180W XPS laser vaporization. Mean preoperative prostate volume was 81 ± 28.7 ml and mean laser time was 28.2 ± 12.5 minutes. No major complications intraoperatively or postoperatively were observed and no blood transfusions were required. Comparing to preoperative characteristics, International Prostate Symptom Score (IPSS), maximum ?ow rate (Qmax) and post-void residual (PVR) parameters were improved signi?cantly and sustained during the follow-up period. At 3, 6 and 12-month follow-ups, mean urinary peak ?ow increased from 6.2 ± 2.1 ml per second to 19.8 ± 4.6, 19.4 ± 4.7 and 19.6 ± 4.9 ml per second, respectively. Mean International Prostate Symptom Scores decreased over time, from 28.9 ± 4.5 to 8.2 ± 1.6, 6.2 ± 1.22 and 5.88 ± 1.15 at 3, 6, 12 months, respectively. Conclusions: 180W XPS Greenlight laser vaporization is a safe and effective treatment option for patients with lower urinary tract symptoms secondary to BPH.
关键词： mini-invasive treatment of BPH,Benign prostatic hyperplasia (BPH),180W XPS Greenlight laser
更新于2025-09-12 10:27:22
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State of the art of Thulium laser enucleation and vapoenucleation of the prostate: a systematic review
摘要： Tm:YAG laser operates at a wavelength of 1940-2013 nm in a continuous wave mode, which enables smooth incision and rapid vaporization of prostatic tissue, with a shallow penetration of only 0.2 mm. These characteristics make Tm:YAG a versatile laser, allowing the surgeon to perform resection, vaporization, and vapoenucleation. This systematic review aims to summarize the current evidence of safety and efficacy, long-term durability, impact on sexual function following Tm:YAG laser enucleation and vapoenucleation of the prostate and to compare the outcomes of these procedures versus other surgical treatments of benign prostatic hyperplasia.
关键词： ThuVEP,ThuLEP,prostatic,laser therapy,complications,patient outcome assessment,hyperplasia
更新于2025-09-12 10:27:22
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Standardization of 532 nm Laser Terminology for Surgery in Benign Prostatic Hyperplasia (BPH): A Systematic Review
摘要： Introduction: The use of GreenLight? laser technology to remove the prostatic transitional zone (TZ) transurethrally has grown considerably in recent years, and with it an increase in the number of terms that are used to describe similar techniques. Varying terminology complicates literature analysis and publication, which can cause confusion when performing reviews of the literature. It has become necessary to simplify and standardize terminology used to describe transurethral prostate debulking procedures using the 532 nm laser in order to simplify communication on these techniques. Materials and Methods: We conducted a search on September 17th, 2019 in the following databases: Ovid MEDLINE?; Ovid EMBASE; and PubMed. Results: Of the 1115 unique records found in our database search, a total of 27 articles were selected for inclusion. Of the 16 search terms used, we found that 4 terms could be used to describe the fundamental technique associated with each search term. These terms include “vaporization”, “vaporesection”, “vapoenucleation”, and “enucleation”. Conclusions: Standardizing terminology leads to an efficient consolidation of terms based on the above outcomes. This will streamline the literature search process for future publications and facilitate comparison of varying techniques.
关键词： vapoenucleation,enucleation,532 nm laser,vaporesection,prostate,terminology,benign prostatic hyperplasia,laser prostatectomy,vaporization,GreenLight laser
更新于2025-09-12 10:27:22
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Novel thulium fiber laser for endoscopic enucleation of the prostate: A prospective comparison with conventional transurethral resection of the prostate
摘要： Objective: To compare the efficacy and safety of a novel thulium fiber laser for endoscopic enucleation of the prostate with monopolar transurethral resection of the prostate in patients with smaller glands (<80 cc). Methods: A total of 51 patients underwent thulium fiber laser enucleation of the prostate, and 52 patients underwent monopolar transurethral resection of the prostate. All patients were assessed preoperatively, and at 3, 6, and 12 months postoperatively (International Prostate Symptom Score, maximum urine flow rate, International Prostate Symptom Score-quality of life). Preoperative prostate volumes and prostate-specific antigen levels were complications were graded according to the Clavien classification. Results: Mean surgery time was longer in the thulium fiber laser enucleation of the prostate group (46.6 ± 10.2 vs 39.9 ± 8.6 min, P < 0.001), while catheterization and hospital stay were greater (P < 0.001). At 12 months, there were no differences in functional outcomes (International Prostate Symptom Score, maximum urine flow rate). Despite comparable prostate volumes at 12 months (P = 0.864), the prostate-specific antigen level in the thulium fiber laser enucleation of the prostate group (0.5 ± 0.5 ng/mL) was lower than in the transurethral resection of the prostate group (1.1 ± 1.0 ng/mL; P < 0.001). Hemoglobin and serum sodium decrease was lower in the thulium fiber laser enucleation of the prostate group (1.01 ± 0.4 g/dL and 1.1 ± 1.1 mmol/L) than in the transurethral resection of the prostate group (1.8 ± 0.8 g/dL and 4.1 ± 1.1 mmol/L; P < 0.001). Urinary incontinence rates at 12 months were comparable (P = 0.316). Conclusions: Thulium fiber laser enucleation of the prostate with novel thulium fiber laser in patients with smaller prostate glands (<80 cc) is comparable to transurethral resection of the prostate in voiding parameters improvement and complication rates. At the same time, the technique allows for a more substantial prostate-specific antigen decrease, indicating more complete removal of adenoma.
关键词： transurethral resection of the prostate,benign prostatic hyperplasia,endoscopic enucleation of the prostate,thulium fiber laser
更新于2025-09-11 14:15:04
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Greenlight laser enucleation of the prostate
摘要： Symptomatic benign prostatic hyperplasia increases greatly in men beginning in the sixth decade of life. The American Urological Association (AUA) and European Association of Urology (EAU) recommend surgical intervention in patients who fail medical therapy [1,2]. The surgical approach is dependent on patient anatomy, patient and surgeon preference, medical comorbidities, as well as surgeon experience and prostate size. Transurethral prostatectomy is historically prostate size-dependent because of irrigant absorption (dilutional hyponatremia) and procedure time [photovaporization of the prostate (PVP)]. Incomplete resection of large adenoma can fail to improve patient symptoms.
关键词： Greenlight laser enucleation of the prostate,surgical intervention,benign prostatic hyperplasia,transurethral prostatectomy
更新于2025-09-11 14:15:04
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Holmium Laser Enucleation of the Prostate: Modified Two-Lobe Technique versus Traditional Three-Lobe Technique—A Randomized Study
摘要： Background. Holmium laser enucleation of the prostate (HoLEP) is considered the standard endoscopic treatment of benign prostatic hyperplasia (BPH), but traditional HoLEP surgery will cause some postoperative complications. This study was attempted to evaluate the safety and efficacy of modified two-lobe technique versus traditional three-lobe technique of HoLEP focusing mainly on incidences of retrograde ejaculation (RE) and urinary incontinence (UI). Methods. From March 2014 to February 2017, 191 men with BPH were randomly assigned to two groups: 97 underwent modified two-lobe technique; 94 underwent traditional three-lobe technique. All patients were followed up for 12 months. Primary outcomes were incidences of RE and UI, and secondary outcomes were international prostate symptom score (IPSS), quality of life (QOL), maximal urine flowing rate (MFR), and residual urine among the studied patients. Results. Compared with the traditional technique, patients in the modified group had a statistically significant decrease in frequency of UI (1.03% vs 8.51%, p = 0.036) and RE in the 6th month (33.33% vs 63.64%, p = 0.030) and 12th month (13.33% vs 50%, p = 0.034) and a significant increase in ejaculatory volume in the 6th month (p = 0.050) and 12th month (p = 0.003). Besides, the modified HoLEP was more beneficial to patients according to the change of QoL score at 1 month (p = 0.002), 3 months (p = 0.004), 6 months (p = 0.026), and 12 months (p = 0.015). Conclusions. The modified two-lobe technology of HoLEP reduced the incidence of RE and UI, which improved the quality of life of the patients after surgery compared to the traditional three-lobe technology. This trial is registered with ChiCTR1800018553.
关键词： urinary incontinence,benign prostatic hyperplasia,Holmium laser enucleation of the prostate,retrograde ejaculation,quality of life
更新于2025-09-11 14:15:04
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Simultaneous 18F-fluciclovine Positron Emission Tomography and Magnetic Resonance Spectroscopic Imaging of Prostate Cancer
摘要： Purpose: To investigate the associations of metabolite levels derived from magnetic resonance spectroscopic imaging (MRSI) and 18F-?uciclovine positron emission tomography (PET) with prostate tissue characteristics. In a cohort of 19 high-risk prostate cancer patients that underwent simultaneous PET/MRI, we evaluated the diagnostic performance of MRSI and PET for discrimination of aggressive cancer lesions from healthy tissue and benign lesions. Data analysis comprised calculations of correlations of mean standardized uptake values (SUVmean), maximum SUV (SUVmax), and the MRSI-derived ratio of (total choline + spermine + creatine) to citrate (CSC/C). Whole-mount histopathology was used as gold standard. Results: The results showed a moderate signi?cant correlation between both SUVmean and SUVmax with CSC/C ratio. Conclusions: We demonstrated that the simultaneous acquisition of 18F-?uciclovine PET and MRSI with an integrated PET/MRI system is feasible and a combination of these imaging modalities has potential to improve the diagnostic sensitivity and speci?city of prostate cancer lesions.
关键词： citrate,benign prostatic hyperplasia,chemical shift imaging,prostate cancer,positron emission tomography,magnetic resonance spectroscopy
更新于2025-09-11 14:15:04