Scaling-up UV-mediated Intramolecular-Photo-Dehydro-Diels-Alder reactions using a Homemade High-Performance Annular Continuous-Flow Reactor

摘要： In this communication, we present a self-made annular continuous-flow reactor, which can be used in the UV/Vis-range in an internal numbering-up manner. As a model reaction, we chose a powerful and batch scale-limited benzoannelation method, which is an intramolecular Photo-Dehydro-Diels-Alder (IMPDDA) reaction. The scaling-up potential of this particular photochemical benchmark reaction towards the preparation of macrocylic (1,7)naphthalenophanes by variation of selected flow parameters is presented.