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[IEEE 2018 43rd International Conference on Infrared, Millimeter, and Terahertz Waves (IRMMW-THz2018) - Nagoya, Japan (2018.9.9-2018.9.14)] 2018 43rd International Conference on Infrared, Millimeter, and Terahertz Waves (IRMMW-THz) - Detection of Human Tumor Markers with THz Metamaterials
摘要: THz bioanalytical techniques are already proven as a viable tool for the label-free detection of biomolecules. But still, significant improvement of THz sensing techniques is needed to reach application relevant sensitivity levels. We present the label-free THz sensing of human tumor markers using a highly sensitive metamaterial based THz biosensor. High affinity binding of the specific protein to DNA is utilized for localized functionalization to further enhance the detection sensitivity.
关键词: tumor markers,DNA-protein interaction,THz sensing,metamaterials,biosensor
更新于2025-09-23 15:21:01
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Ultrahigh Q-factor dual-band terahertz perfect absorber with dielectric grating slit waveguide for sensing
摘要: Terahertz (THz) perfect absorber with ultra-narrow bandwidth at near-unity absorbance has been a challenging issue due to mutual restriction of elemental requirements in design. Here, we propose an extremely sharp dual-band THz perfect absorber with ultrahigh Q-factor and near-unity absorbance by incorporating a Fabry-Perot micro-cavity into dielectric grating slit waveguide. Full-wave simulation demonstrates that the proposed structure not only achieves ultra-narrow band perfect absorption with an ultrahigh Q-factor of 4600 in THz regime, but also shows extraordinary sensing performance with a record figure of merit (FOM) of 2415 at THz frequencies. The optimized guided mode resonance leads to the ultrahigh Q-factor through suppressing the absorption and radiation losses. The enhanced interaction between the cavity localized fields and the analytes significantly improves THz sensing capability. Our design approach shows a promising future in simple and inexpensive THz biochemical sensors.
关键词: THz sensing,Terahertz wave,perfect absorber,ultrahigh Q-factor
更新于2025-09-19 17:13:59
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[IEEE 2019 IEEE 6th International Symposium on Electromagnetic Compatibility (ISEMC) - Nanjing, China (2019.11.1-2019.11.4)] 2019 IEEE 6th International Symposium on Electromagnetic Compatibility (ISEMC) - Spoof Plasmon Resonance with Terahertz 1-D Periodic Rectangular Filled Refractive Index Sensor
摘要: the dispersion properties of spoof surface plasmon polaritons with 1D rectangular groove structure by analytical solution and numerical solution respectively is analyzed, and the FEM method was used to simulate the refractive index sensing of SPR in terahertz band in an Otto configuration. From the simulation results, we can see that the 1D periodic groove has strong field constraint ability in THz regime as well as in optical band, and the variation of reflection coefficient with incident angle and frequency is very sensitive to the refractive index of the analyte. These results provide a new approach to sample detection and THz regime refractive index sensing, which has great advantages in biomedical tissue detection and sample detection in the future.
关键词: FEM,Spoof Spps,dispersion,THz sensing,groove
更新于2025-09-19 17:13:59