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Long tapered fiber with array of FBG
摘要： A tapered optical fiber with an adiabatic transition from single-mode to a few-mode part has been fabricated with an array of fiber Bragg gratings being inscribed during the drawing process. We demonstrate that the propagating optical signal remains single-mode along the tapered fiber FBG array even in a multimode part of it. The spectral width of the reflected signal from the tapered optical fiber is 4 nm. The level of the reflected signal is up to 5% at some wavelengths.
关键词： Tapered optical fibers,Fiber optics sensors,Fiber Bragg gratings
更新于2025-11-28 14:23:57
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Depth-resolved fiber photometry with a single tapered optical fiber implant
摘要： Fiber photometry is increasingly utilized to monitor fluorescent sensors of neural activity in the brain. However, most implementations are based on flat-cleaved optical fibers that can only interface with shallow tissue volumes adjacent to the fiber. We exploit modal properties of tapered optical fibers (TFs) to enable light collection over an extent of up to 2 mm of tissue and multisite photometry along the taper. Using a single TF, we simultaneously observed distinct dopamine transients in dorsal and ventral striatum in freely moving mice performing a simple, operant conditioning task. Collection volumes from TFs can also be engineered in both shape and size by microstructuring the nonplanar surface of the taper, to optically target multiple sites not only in the deep brain but, in general, in any biological system or organ in which light collection is beneficial but challenging because of light scattering and absorption.
关键词： neural activity,tapered optical fibers,dopamine transients,fiber photometry,multisite photometry
更新于2025-09-16 10:30:52