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Application of quantitative light-induced fluorescence technology for tooth bleaching treatment and its assessment: An in vitro study
摘要： Objectives: This study aimed to determine the effectiveness of combination of photocatalysts - low concentration of hydrogen peroxide (3.5%) and titanium dioxide (TiO2), activated at a wavelength of 405 nm using quantitative light-induced fluorescence (QLF) technology, and to quantify the tooth-bleaching effect using fluorescence images from QLF technology. Materials and Methods: Forty bovine incisors were extrinsically stained according to Stookey’s method. Two bleaching solutions were prepared by mixing 3.5% H2O2 with 0.05% of anatase and rutile nano-TiO2 powder. These solutions were applied to the stained teeth using a micro-brush and then irradiated for 15 minutes at either 306 or 405 nm to activate the bleaching agent. The color difference was assessed before and after every 5 minutes of treatment. The ?E and ?F were obtained from white-light and fluorescence images, respectively. Results: All the low H2O2/TiO2 treatments caused significant bleaching after irradiation at 306 and 405 nm (p<0.05). There was no significant difference between the wavelengths (p>0.05), but a greater bleaching effect was obtained with anatase-TiO2 at 306 nm and rutile-TiO2 at 405 nm. Analysis of the fluorescence images revealed that the ?F values decreased significantly in all the groups according to the treatment times (p<0.05). There was a statistically significant reverse correlation between ?E and ??F (r= -0.822, p<0.001). Conclusions: Low H2O2/TiO2 with 405 nm of QLF technology demonstrated greater bleaching effect. Furthermore, the fluorescent images from QLF technology showed a possibility for assessment of tooth bleaching.
关键词： Digital imaging,Tooth bleaching,Theragnosis,405 nm wavelength,Titanium dioxide,Quantitative light-induced fluorescence (QLF)
更新于2025-09-23 15:23:52
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Cobalt/Manganese Oxides as Theragnosis Nanoplatforms With Magnetic Resonance/Near-Infrared Imaging for Efficient Photothermal Therapy of Tumors
摘要： The combination of near-infrared (NIR) response and imaging response is a hot research area in which the functions of nanomaterials are maximized. However, the types of such materials reported so far present problems such as requiring complex synthesis. In this study, hydrophilic, porous, and hollow cobalt/manganese oxide (CMO) nanocrystals (NCs) were successfully prepared via a facile and green hydrothermal route. The CMO NCs show strong near-infrared (NIR) absorption, which results from their defect structure due to the coexistence of Co2+ and Co3+ in the as-prepared CMO NCs. Thus, the CMO NCs exhibit excellent photothermal performance, showing photothermal efficiency of up to 43.2%. In addition, the CMO NCs possess good magnetic resonance (MR) imaging performance, with longitudinal relaxivity (r1) of up to 3.48 mM?1 s?1. Finally, for the first time, we prove that the CMO nanocrystals are a promising photothermal agent. Our work provides insights into the application of Mn-based control agents and photothermal agents for photothermal theragnosis therapy.
关键词： cobalt/manganese oxides,photothermal agents,magnetic resonance imaging,photothermal theragnosis therapy,near-infrared absorption
更新于2025-09-16 10:30:52