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The first deaf-blind patient in Russia with Argus II retinal prosthesis system. What he sees and why
摘要： A 59-year-old man with retinitis pigmentosa and hearing loss (clinical Usher syndrome) underwent surgery to implant the Argus II retinal prosthesis system in the right eye. This is the first case of retinal implant surgery in the Russian Federation. In this study we propose a new method for evaluating the functional results after implantation of the Argus II, the statistical analysis was performed to find correlations between the sizes of phosphenes that the patient drew and then were digitalized, and the height of the subimplant interface, retinal thickness, impedance, and perceptual threshold, which showed interesting mixed results. Correlation analysis showed the weak dependency between the size of a phosphene and the perceptual threshold and we did not find significant correlations between a phosphene and the height of the interface, impedance and retinal thickness.
关键词： Argus II,Usher syndrome,retinitis pigmentosa,deaf-blind,blind,artificial vision,retinal prosthesis system,retinal implant,deafblind
更新于2025-09-23 15:23:52
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Improvement in reading performance through training with simulated thalamic visual prostheses
摘要： Simulations of artificial vision are used to provide the researcher an opportunity to explore different aspects of visual prosthesis device design by observing subject performance on various tasks viewed through the simulation. Such studies typically use normal, sighted subjects to measure performance at a given point in time. Relatively few studies examine performance changes longitudinally to quantitatively assess the benefits from a training plan that would be akin to post-implantation rehabilitation. Here, we had six normal, sighted subjects use a standard reading task with daily practice over eight weeks to understand the effects of an intensive training schedule on adaptation to artificial sight. Subjects read 40 MNREAD-style sentences per session, with a new set each session, that were presented at five font sizes (logMAR 1.0–1.4) and through three center-weighted phosphene patterns (2,000, 1,000, 500 phosphenes). We found that subjects improved their reading accuracy across sessions, and that the training lead to an increase of reading speed that was equivalent to a doubling of available phosphenes. Most importantly, the hardest condition, while initially illegible, supported functional reading after training. Consistent with experience-driven neuroplastic changes, gaps in the training schedule lead to transient decreases in reading speed, but, surprisingly, not reading accuracy. Our findings contribute to our larger project of developing a thalamic visual prosthesis and to post-implant rehabilitation strategies.
关键词： training,simulation,rehabilitation,artificial vision,reading performance,visual prosthesis,phosphene patterns
更新于2025-09-23 15:23:52