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Investigation of out-of-plane motion artifacts in two-dimensional noninvasive vascular ultrasound elastography
摘要: Ultrasound noninvasive vascular elastography (NIVE) has shown its potential to measure strains of carotid arteries to predict plaque instability. When two-dimensional (2-D) strain estimation is performed, either in longitudinal or cross-sectional view, only in-plane motions are considered. The motions in elevation direction (i.e., perpendicular to the imaging plane), can induce estimation artifacts affecting the accuracy of 2-D NIVE. The influence of such out-of-plane motions on the performance of axial strain and axial shear strain estimations has been evaluated in this study. For this purpose, we designed a diseased carotid bifurcation phantom with a 70% stenosis and an in vitro experimental setup to simulate orthogonal out-of-plane motions of 1 mm, 2 mm and 3 mm. The Lagrangian speckle model estimator (LSME) was used to estimate axial strains and shears under pulsatile conditions. As anticipated, in vitro results showed more strain estimation artifacts with increasing magnitudes of motions in elevation. However, even with an out-of-plane motion of 2.0 mm, strain and shear estimations having inter-frame correlation coefficients higher than 0.85 were obtained. To verify findings of in vitro experiments, a clinical LSME dataset obtained from 18 participants with carotid artery stenosis was used. Deduced out-of-plane motions (ranging from 0.25 mm to 1.04 mm) of the clinical dataset were classified into three groups: small, moderate and large elevational motions. Clinical results showed that pulsatile time-varying strains and shears remained reproducible for all motion categories since inter-frame correlation coefficients were higher than 0.70, and normalized cross-correlations between radiofrequency images were above 0.93. In summary, the performance of LSME axial strain and shear estimations appeared robust in the presence of out-of-plane motions (< 2 mm) as encountered during clinical ultrasound imaging.
关键词: ultrasound elastography,out-of-plane motion,carotid bifurcation phantom
更新于2025-09-10 09:29:36
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Instant Stent-Accentuated Three-Dimensional Optical Coherence Tomography Guided Selection of Proper Distal Cell for Side Branch Dilatation in Bifurcation Stenting
摘要: In the bifurcation stenting, the distal rewiring for the side branch postdilatation confirmed by two-dimensional modalities may not lead to favorable results in some cases. If there are two distal cells divided by the link bridging from the carina, the rewiring through the larger distal cell may be recommended for the side branch postdilatation. Detailed confirmation of the rewired cell by the intraprocedural instant stent-accentuated three-dimensional optical coherence tomography is important.
关键词: distal rewiring,bifurcation stenting,side branch postdilatation,instant stent-accentuated 3D-OCT,three-dimensional optical coherence tomography
更新于2025-09-09 09:28:46
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On the numerical investigation of size and surface effects on nonlinear dynamics of a nanoresonator under electrostatic actuation
摘要: This study aims to investigate the influences of nanostructure parameter and surface elasticity parameters on the nonlinear vibration of a nanoelectromechanical system under double-sided electrostatic actuation. For this, the effects of size dependency and surface energy are modeled through applying the consistent couple-stress theory together with the Gurtin–Murdoch elasticity theory. Taking into account the midplane stretching effect for doubly clamped boundary conditions, the nonlinear strain–displacement relationship is considered based on the Euler–Bernoulli beam assumption. Hamilton’s principle is utilized in order to establish the governing differential motion’s equation, and reduced-order model is obtained through implementing Galerkin’s procedure. Bifurcation diagrams are plotted to capture the steady-state response of the system with varying the nondimensional parameter, the ratio of AC to DC voltage amplitude. The influences of the length-scale parameter, surface elasticity modulus and density, and residual surface stress on the system dynamic response have been explored. The results reveal that the pull-in excitation frequency is highly influenced by these parameters, and also the interval length of the bifurcation parameter corresponding to the periodic and chaotic motions is extremely shifted by the amount of couple-stress and residual surface stress parameters.
关键词: Size-dependent NEMS,Chaos,Bifurcation,Surface effects
更新于2025-09-09 09:28:46