- 标题
- 摘要
- 关键词
- 实验方案
- 产品
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Detection of divalent copper with improved accuracy by dual suppression of electrochemiluminescent recovery
摘要： This work is to construct an electrochemiluminescent (ECL) sensor with improved accuracy for the detection of Cu2+. The improved accuracy is achieved by utilizing a reaction system to realize Cu2+ dose-dependent dual suppression of ECL recovery from gold nanoparticle-graphitic carbon nitride nanosheet nanohybrid (Au-CNNS) film. The ECL sensor shows sensitive response to Cu2+ in the concentration range of 5 nM to 500 nM with an enlarged slope, and high specificity attributed to the high affinity of CNNS-Cu2+ complex and the high catalytic activity of Cu(NH3)6 2+ to decompose H2O2 in the reaction system. The proposed ECL sensor with improved accuracy may prove valuable in future biomedical applications.
关键词： dual suppression,electrochemiluminescent sensor,copper,graphitic carbon nitride nanosheets
更新于2025-09-23 15:23:52
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Sandwich-type signal-off photoelectrochemical immunosensor based on dual suppression effect of PbS quantum dots/Co3O4 polyhedron as signal amplification for procalcitonin detection
摘要： A novel signal-off photoelectrochemical (PEC) immunosensor was proposed for procalcitonin (PCT) sensitive detection based on the Au nanoparticles/BiOI nanosheets/Black TiO2 nanoparticles (Au NPs/BiOI NSs/B-TiO2 NPs) as photoactive matrix and PbS quantum dots/Co3O4 polyhedron (PbS/Co3O4) as a quenching signal label for signal amplification. Concretely, BiOI NSs was fabricated by successive ionic layer absorption and reaction (SILAR) and formed the interlaced flake-like structure. Then Au NPs dropped on the BiOI NSs/B-TiO2 NPs electrode forming Au NPs/BiOI NSs/B-TiO2 NPs sensitization structure, which increased the utilization of visible light and accelerated electron transfer rate, resulting in a desirable PEC signal. PbS/Co3O4, an effective dual suppression signal quencher, was proposed for signal-off PEC immunosensor to weaken the photocurrent response because of the steric impedance, competitive absorption of light and competing consumption of electron donor. In this proposal, PCT was chosen to measure the performance of the suggested PEC immunosensor. Consequently, the fabricated PEC immunosensor showed a widely detection ranged from 0.1 pg/mL to 50 ng/mL and a low detection limit of 0.02 pg/mL (S/N = 3). What is more, the proposed PEC immunosensor possessed satisfactory selectivity, stability and reproducibility.
关键词： Dual suppression effect,Procalcitonin,Photoelectrochemical immunosensor,Signal-off
更新于2025-09-11 14:15:04