Multimodal Laser Stimulation and Traditional Needle Acupuncture in Post-Stroke Patients—A Pilot Cross-Over Study with Results from Near Infrared Spectroscopy

摘要： Background: The objective of this pilot study was to evaluate the cerebral e?ects of laser stimulation and traditional needle acupuncture in patients after stroke. Methods: Seventeen stroke patients (12 female and ?ve male; mean age ± SD: 66.5 ± 12.9 years) were randomly selected in a stroke rehabilitation hospital. Patients’ regional cerebral blood oxygen saturation (rSO2) values were recorded before, during, and after needle acupuncture (scalp, ear and body) as well as before, during, and after corresponding laser stimulation (red laser, four points: 100 mW, 658 nm, 500 μm; yellow laser, one point: 50 mW, 589 nm, 500 μm; infrared laser, three points: 100 mW, 810 nm, 500 μm; green laser, one point: 5 mW, 532 nm, 500 μm) in a cross-over study design. Results: There were no signi?cant changes after needle acupuncture in the phases immediately after needle insertion or during acupuncture stimulation. However, after manual needle acupuncture and after laser stimulation, the majority of the rSO2 values showed increases. The highest value (+3%) was reached after laser stimulation treatment. Heart rate and blood pressure before and after the treatments did not show signi?cant alterations. Conclusions: Changes in local cerebral oxygen saturation could be quanti?ed, although con?rmation may only be expected after extensive follow-up studies.