Hybrid Fractional Ablative and Nonablative Laser Resurfacing of Actinic Keratoses

摘要： Field treatment of actinic keratoses (AKs) is a therapeutic challenge due to lack of patient tolerability and compliance with traditional treatments. Actinic keratoses are a known risk factor for development of squamous cell carcinoma. Actinic keratoses may be treated with cryosurgery, topical immunomodulators, topical chemotherapy, electrodessication and curettage, and photodynamic therapy. Both cryosurgery and curettage can leave unsightly scars or permanent dyspigmentation. Topical immunomodulators and topical chemotherapy require patient compliance. Photodynamic therapy can be painful and requires strict sunlight avoidance. Laser resurfacing is emerging as a promising therapeutic option for AKs with low recurrence rate after treatment.1–4 We present a single treatment with a hybrid 1,470-nm diode/2,940-nm Er:YAG fractional laser (Halo; Sciton, Palo Alto, CA) as a novel method to treat AKs off the face.