Raman spectroscopy for kidney tissue and its neoplasms research

摘要： This work is devoted to the study of the spectral properties of intact and tumor kidney tissues. For excitation of Raman scattering and autofluorescence a laser with a wavelength of 785 nm was used. Visually and morphologically unchanged tissues of pig and human kidneys as well as tumor tissue of human kidneys were used as the test samples. The analysis of registered signals was carried out using the method of projection on latent structures to isolate the spectral features between tissue types. The study showed a difference between the registered signals of the clear cell adenocarcinoma and chromophobe types of human kidney cancer, the most informative bands of the Raman spectrum for the determination of the clear cell human kidney cancer were 330-500 cm-1, 870-980 cm-1, 980-1130 cm-1, 1230-1270 cm-1, 1360 -1420 cm-1.