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Advanced Silicon Carbide Devices and Processing || Silicon Carbide for Novel Quantum Technology Devices
摘要： Silicon carbide (SiC) has recently been investigated as an alternative material to host deep optically active defects suitable for optical and spin quantum bits. This material presents a unique opportunity to realise more advanced quantum-based devices and sensors than currently possible. We will summarise key results revealing the role that defects have played in enabling optical and spin quantum measurements in this material such as single photon emission and optical spin control. The great advantage of SiC lies in its existing and well-developed device processing protocols and the possibilities to integrate these defects in a straightforward manner. There is particular current interest in nanomaterials and nanophotonics in SiC that could, once realised, introduce a new platform for quantum nanophotonics and in general for photonics. We will summarise SiC nanostructures exhibiting optical emission due to multiple polytypic bandgap engineering and deep defects. The combination of nanostructures and in-built paramagnetic defects in SiC could pave the way for future single-particle and single-defect quantum devices and related biomedical sensors with single-molecule sensitivity. We will review relevant classical devices in SiC (photonic crystal cavities, microdiscs) integrated with intrinsic defects. Finally, we will provide an outlook on future sensors that could arise from the integration of paramagnetic defects in SiC nanostructures and devices.
关键词： Optical-detected magnetic resonance,Single-photon sources,Silicon carbide deep defects,Paramagnetic properties
更新于2025-09-23 15:22:29
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A novel bioreactor for combined magnetic resonance spectroscopy and optical imaging of metabolism in 3D cell cultures
摘要： Purpose: Fluorescence lifetime imaging microscopy (FLIM) of endogenous fluorescent metabolites permits the measurement of cellular metabolism in cell, tissue and animal models. In parallel, magnetic resonance spectroscopy (MRS) of dynamic nuclear (hyper)polarized 13C‐pyruvate enables measurement of metabolism at larger in vivo scales. Presented here are the design and initial application of a bioreactor that connects these 2 metabolic imaging modalities in vitro, using 3D cell cultures. Methods: The model fitting for FLIM data analysis and the theory behind a model for the diffusion of pyruvate into a collagen gel are detailed. The device is MRI‐compatible, including an optical window, a temperature control system and an injection port for the introduction of contrast agents. Three‐dimensional printing, computer numerical control machining and laser cutting were used to fabricate custom parts. Results: Performance of the bioreactor is demonstrated for 4 T1 murine breast cancer cells under glucose deprivation. Mean nicotinamide adenine dinucleotide (NADH) fluorescence lifetimes were 10% longer and hyperpolarized 13C lactate:pyruvate (Lac:Pyr) ratios were 60% lower for glucose‐deprived 4 T1 cells compared to 4 T1 cells in normal medium. Looking at the individual components of the NADH fluorescent lifetime, τ1 (free NADH) showed no significant change, while τ2 (bound NADH) showed a significant increase, suggesting that the increase in mean lifetime was due to a change in bound NADH. Conclusion: A novel bioreactor that is compatible with, and can exploit the benefits of, both FLIM and 13C MRS in 3D cell cultures for studies of cell metabolism has been designed and applied.
关键词： multimodal,optical imaging,bioreactor,magnetic resonance spectroscopy (MRS),nicotinamide adenine dinucleotide (NADH),metabolism,fluorescence lifetime imaging (FLIM),lactate production
更新于2025-09-23 15:22:29
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Epitaxial Growth of Orthorhombic GaFeO3 Thin Films on SrTiO3 (111) Substrates by Simple Sol-Gel Method
摘要： A Sol-gel method assisted with spin-coating has been successfully used to grow orthorhombic GaFeO3 epitaxial films on SrTiO3 (111) substrates for the first time. The film with Pna21 crystal structure has been grown along the c-axis. The rocking curve of (004) reflection shows that the Full-Width at Half-Maximum (FWHM) value could be determined to be 0.230°, indicating good single crystallinity and high quality. X-ray Φ scan reveals a three-fold symmetry of the substrate and a six-fold symmetry of the film, respectively. The in-plane domains rotate 60° from each other in the film. Uniform film with dense structure, columnar grains with similar grain size was obtained. The thickness of the film was evaluated to be ~170 nm. The roughness value (RMS) measured by AFM was 4.5 nm, revealing a flat film. The in-plane Magnetization versus Magnetic field (M-H) curve at 5 K performs a typical ferri- or ferromagnetic hysteresis loop with a saturated magnetization (Ms) value of 136 emu/cm3. The Curie temperature could be determined to be 174 K. Compared to Pulsed Laser Deposition (PLD), the sol-gel method can prepare large area films with low cost. These new films show promising applications in multiferroic devices.
关键词： GaFeO3 film,magnetic property,sol-gel method,multi-domain structure,epitaxial growth
更新于2025-09-23 15:22:29
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Linear Polarization Features in the Quiet-Sun Photosphere: Structure and Dynamics
摘要： We present detailed characteristics of linear polarization features (LPFs) in the quiet-Sun photosphere from high-resolution observations obtained with SUNRISE/IMaX. We explore differently treated data with various noise levels in linear polarization signals, from which structure and dynamics of the LPFs are studied. Physical properties of the detected LPFs are also obtained from the results of Stokes inversions. The number of LPFs and their sizes and polarization signals are found to be strongly dependent on the noise level and on the spatial resolution. While the linear polarization with a signal-to-noise ratio ≥ 4.5 covers about 26% of the entire area in the least noisy data in our study (with a noise level of 1.7 × 10?? in the unit of Stokes I continuum), the detected (spatially resolved) LPFs cover about 10% of the area at any given time, with an occurrence rate on the order of 8 × 10?3 s?1 arcsec?2. The LPFs were found to be short lived (in the range of 30 – 300 s), relatively small structures (radii of ≈ 0.1 – 1.5 arcsec), highly inclined, posing hG fields, and they move with an average horizontal speed of 1.2 km s?1. The LPFs were observed (almost) equally on both upflow and downflow regions, with an intensity contrast always larger than that of the average quiet Sun.
关键词： Photosphere: polarization,Magnetic fields,Optical
更新于2025-09-23 15:22:29
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Turn-On Fluorescence Aptasensor on Magnetic Nanobeads for Aflatoxin M1 Detection Based on an Exonuclease III-Assisted Signal Amplification Strategy
摘要： In order to satisfy the need for sensitive detection of Aflatoxin M1 (AFM1), we constructed a simple and signal-on fluorescence aptasensor based on an autocatalytic Exonuclease III (Exo III)-assisted signal amplification strategy. In this sensor, the DNA hybridization on magnetic nanobeads could be triggered by the target AFM1, resulting in the release of a single-stranded DNA to induce an Exo III-assisted signal amplification, in which numerous G-quadruplex structures would be produced and then associated with the fluorescent dye to generate significantly amplified fluorescence signals resulting in the increased sensitivity. Under the optimized conditions, this aptasensor was able to detect AFM1 with a practical detection limit of 9.73 ng kg?1 in milk samples. Furthermore, the prepared sensor was successfully used for detection of AFM1 in the commercially available milk samples with the recovery percentages ranging from 80.13% to 108.67%. Also, the sensor performance was evaluated by the commercial immunoassay kit with satisfactory results.
关键词： aptasensors,signal amplification,G-quadruplex,magnetic nanobeads,aflatoxin M1
更新于2025-09-23 15:22:29
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Towards Real-time Metabolic Profiling of Cancer with Hyperpolarized Succinate
摘要： Purpose: The energy-yielding mitochondrial Krebs cycle has been shown in many cancers and other diseases to be inhibited or mutated. In most cells, the Krebs cycle with oxidative phosphorylation generates approximately 90% of the adenosine triphosphate in the cell. We designed and hyperpolarized carbon-13 labeled succinate (SUC) and its derivative diethyl succinate (DES) to interrogate the Krebs cycle in real-time in cancer animal models. Procedures: Using Parahydrogen Induced Polarization (PHIP), we generated hyperpolarized SUC and DES by hydrogenating their respective fumarate precursors. DES and SUC metabolism was studied in five cancer allograft animal models: breast (4T1), Renal Cell Carcinoma (RENCA), colon (CT26), lymphoma NSO, and lymphoma A20. Results: The extent of hyperpolarization was 8 ± 2% for SUC and 2.1 ± 0.6% for DES. The metabolism of DES and SUC in the Krebs cycle could be followed in animals 5 s after tail vein injection. The biodistribution of the compounds was observed using 13C FISP imaging. We observed significant differences in uptake and conversion of both compounds in different cell types both in vivo and in vitro. Conclusion: With hyperpolarized DES and SUC, we are able to meet many of the requirements for a useable in vivo metabolic imaging compound – high polarization, relatively long T1 values, low toxicity and high water solubility. However, succinate and its derivative DES are metabolized robustly by RENCA but not by the other cancer models. Our results underscore the heterogeneity of cancer cells and the role cellular uptake plays in hyperpolarized metabolic spectroscopy.
关键词： krebs cycle,hyperpolarization,metabolic imaging,succinate,magnetic resonance spectroscopy
更新于2025-09-23 15:22:29
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Half-metallic ferromagnetic behavior in (Ga, Cr)N and (Ga, Cr, V)N compounds for spintronic technologies: Ab-initio and Monte Carlo methods
摘要： In this article, we investigate the magnetic- and electronic-proprieties of GaN doped with simple- and double-impurities utilizing Ab-initio and Monte Carlo studies. We have predicted that (Ga, Cr)N and (Ga, Cr, V)N compounds exhibit ferromagnetic- and halfmetallic-behavior with 100% spin-polarization at the Fermi-level. Moreover, we have found that Ga1-xCrxN and Ga1-2xCrxVxN (x = 0.04, 0.05 and 0.06) show a 2nd order ferromagnetic transition and that their Tc is above room temperature. These predictions make (Ga, Cr)N and (Ga, Cr, V)N compounds strong-candidates for spintronic-technologies.
关键词： Ab-initio calculations,Monte Carlo method,Diluted magnetic semiconductors,Spintronic,Gallium Nitride
更新于2025-09-23 15:22:29
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Enhanced Photocatalytic Hydrogen Evolution with TiO <sub/>2</sub> -TiN Nanoparticle Composites
摘要： Metal nitrides have potential in energy applications due to their physical and optical properties. Nanoparticle composites of titanium nitride (TiN) and titanium dioxide (TiO2) were investigated for their photocatalytic hydrogen (H2) activity via methanol reformation. Physical mixing of the nanoparticulate TiO2 and TiN was employed to prevent the oxy-nitride formation and particle aggregation observed in thermal preparations. This convenient combination of TiO2 and TiN demonstrated a substantial synergistic effect with enhanced activity (9.4 μmol/h TiO2-TiN vs 1.8 μmol/h TiO2) under combined UV/Vis light. Irradiation under only UV light resulted in a similar enhancement factor compared to using combined UV/Vis light, demonstrating that the enhanced activity of the composites occurs essentially for UV-driven photocatalysis. No activity/enhancement was observed with only visible light irradiation, however, minor enhancement was observed when switching between UV and UV/Vis irradiation, suggesting a contribution from the TiN plasmon. We propose that the plasmonic contribution is dependent on the band gap excitation of TiO2, which reduces the degree of band bending at the TiO2/TiN interface. This promotes the migration of hot electrons from TiN away from the TiO2/TiN interface to be used for H2 evolution.
关键词： TiO2-TiN Nanoparticle Composites,Plasmonics,Optical,Magnetic,and Hybrid Materials,Photocatalytic Hydrogen Evolution
更新于2025-09-23 15:22:29
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Decreased Energy Gap and Enhanced Conductivity in Zn-Doped Sr2IrO4
摘要： The 5d transition metal oxide Sr2IrO4 has attracted much interest in the high-temperature superconductivity community since it highly resembles the cuprate superconductor in crystal and electronic structures. Here, we report on the transport and magnetic properties of Zn-doped Sr2IrO4. It is found that the energy gap of Sr2IrO4 is rapidly decreased with a small amount of Zn doping. Consequently, the electrical conductivity is significantly enhanced. The present work could serve as the prerequisite stage in exploring the possible superconductivity of the Sr2IrO4 compound.
关键词： Energy gap,Magnetic moment,Sr2IrO4
更新于2025-09-23 15:22:29
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[IEEE 2018 IEEE 6th Workshop on Advances in Information, Electronic and Electrical Engineering (AIEEE) - Vilnius, Lithuania (2018.11.8-2018.11.10)] 2018 IEEE 6th Workshop on Advances in Information, Electronic and Electrical Engineering (AIEEE) - 18-pulse Rectifier with Electronic Phase Shifting with Autotransformer in Inverter and Rectifier Mode
摘要： To reduce harmonic distortion of the input current, multipulse rectifiers are used. They require the presence of phase-shifting transformers or autotransformers. Elimination of electromagnetic phase-shifting devices while maintaining small harmonic distortion of the input current and obtaining a power factor close to unity is possible with the use of electronic phase shift. The electronic phase shift is realized by means of the rectifier itself: the introduction of positive and negative control angles in the pairs of rectifiers’ modules. At present, 12-pulse rectifiers with electronic phase shift are known. Unlike classic rectifiers, they do not use phase-shifting transformers and have a unit power factor. Increasing of the rectifier’s pulse makes it possible to improve the harmonic composition of the input current. The use of the principle of electronic phase shift in 18-pulse rectifier leads to different levels of constant voltage at the output of the rectifiers. In this case, to equalize the currents of rectifiers’ modules, one can use both an increase the voltage at the input of rectifiers operating with large control angles and a decrease the input voltage of the rectifiers operating with smaller control angles. The principles of constructing of matching autotransformers for the 18-pulse rectifier with an electronic phase shift are considered in the article. Comparison of 18-pulse rectifiers with use of step-up and step-down autotransformers is made. Data on the installed capacity of autotransformers, power losses are obtained. The results of thermophysical modeling are presented. When comparing the parameters of the matching magnetic elements, it can be concluded that it is more appropriate to use a step-down autotransformer.
关键词： pulse-width modulation,magnetic elements,electronic phase shifting,rectifiers,power factor
更新于2025-09-23 15:22:29