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- 2019
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- electromagnetic pulse
- cell proliferation
- cell membrane permeability
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- apoptosis
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- periodic structures
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- Optoelectronic Information Science and Engineering
- Intelligent Medical Engineering
- Southern University of Science and Technology
- Politehnica University of Timi?oara
- Wroclaw University of Technology
- Centro de laseres pulsados
- Szchenyi Istvn University
- ELI-ALPS, ELI-HU Non-Profit Ltd.
- V.N. Karazin Kharkiv National University
- Politecnico di Torino
- Centro de laseres pulsados and University of Salamanca
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The MOTH II Doppler-Magnetographs and Data Calibration Pipeline
摘要： The calibration pipeline of the level zero images obtained from the Magneto-Optical filters at Two Heights (MOTH II) instrument is presented. MOTH II consists of two 20 cm aperture instruments, each using a Magneto-Optical Filter (MOF): one at 5896 ? (Na D2-line), the other one at 7700 ? (K I-line). MOTH II instruments thus provide full disk line-of-sight Doppler velocity and magnetic field measurements at two heights in the solar atmosphere. The developed MOTH II pipeline employs a set of standard calibration corrections, a correction for signal leakage, due to the non-ideal behavior of the polarizers, and the geometrical registration between the eight images acquired by four CMOS cameras, relative to two components of the signal in two circular polarization states, in each of the two channels. MOTH II data are used to investigate atmospheric dynamics (e.g., internal gravity waves and magneto-acoustic portals) and Space Weather phenomena. Particularly, flare forecasting algorithms, based on the detection of magnetic active regions (ARs) and associated flare probability estimation, are currently under development. The possible matching of MOTH II data with SDO/HMI and SDO/AIA images into a flux rope model, developed in collaboration between Harvard-Smithsonian CfA and MIT Laboratory for Nuclear Science, is being tested.
关键词： polarimetric,solar atmosphere,magnetic fields,helioseismology,spectrographs
更新于2025-09-04 15:30:14
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Comparison of different treatment schemes in 5-ALA interstitial photodynamic therapy for high-grade glioma in a preclinical model: An MRI study
摘要： Background: There is currently no therapy that prevents high-grade glioma recurrence. Thus, these primary brain tumors have unfavorable outcomes. Recently, 5-ALA photodynamic therapy (PDT) has been proposed to delay relapse and is highly expected to have potential synergistic effects with the current standard of care. However, PDT treatment delivery needs to be optimized by evaluating the impact of both the number of fractions and the light power used. Objectives: Our study aimed to compare MRI markers across different treatment schemes that use interstitial PDT in high-grade glioma in a preclinical model. Materials and Methods: Forty-eight “nude” rats were grafted with human U87 cells into the right putamen and subsequently submitted to interstitial PDT. The rats were randomized into six groups, including two different sham groups and four different treated groups (5 fractions at 5 mW or 30 mW and 2 fractions at 5 mW or 30 mW). After photosensitizer (PS) precursor (5-ALA) intake, an optical fiber was introduced into the tumor. Treatment effects were assessed with early high-field MRI to acquire T1 and T2 diffusion and perfusion images. Results: There was no difference in the variation of the diffusion coefficient among the six groups (p=0.0549, Kruskal-Wallis test). However, a significant difference was identified among the six groups in terms of variation in perfusion (p=0.048, Kruskal-Wallis test), supporting a lesional effect in the treated groups. Additionally, the sham groups had significantly smaller edema volumes than were observed in the treated groups. Moreover, the 5-fraction group treated with 30 mW was associated with edema volumes that were significantly greater than those in the 5-fraction group treated with 5 mW (p=0.019). Conclusion: Based on observations of MRI data and considering treatment effects, the 5-fraction group treated at 5 mW was not significantly different from the other treated groups in terms of cell deaths, characterized by diffusion imaging, or necrosis level. However, the significantly lower level of edema observed in this group indicated that this treatment scheme had limited toxicity.
关键词： Glioblastoma,Photodynamic Therapy,High-Grade Glioma,PDT,PpIX,MRI,5-ALA,Magnetic Resonance Imaging
更新于2025-09-04 15:30:14
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Syntheses, structures, photoluminescence, and magnetism of a series of 3,5-di(3,4-dicarboxylphenyloxy)benzoate-based complexes tuned by N-donor co-ligands and transition metal ions
摘要： Six transition metal–organic complexes based on 3,5-di(3,4-dicarboxylphenyloxy)benzoic acid (H5L) and different N-donor co-ligands, namely, Cu(H3L)(2,20-bpy)(cid:2)H2O (1), Zn2(HL)(2,20-bpy)2 (2), Cd2(HL)(2,20-bpy)2(H2O) (3), Cd2(HL)(phen)4(cid:2)5H2O (4), Cu(H3L)(phen) (5), and Cu(H3L)(4,40-bpy)(cid:2)H2O (6) (2,20-bpy = 2,20-bipyridine, phen = 1,10-phenanthroline, 4,40-bpy = 4,40-bipyridine), were successfully synthesized under hydrothermal conditions. Their structures were determined by single-crystal X-ray diffraction analyses and further characterized by elemental analyses, IR, powder X-ray diffraction (PXRD), and thermogravimetric analyses (TGA). Complexes 1 and 5 possess discrete zero-dimensional (0D) structures which are further assembled into three-dimensional (3D) supramolecular frameworks by hydrogen-bonding interactions and p–p stacking interactions. Complexes 2 and 3 display similar 3D frameworks with different topologies. Complex 4 shows a one-dimensional (1D) chain which is further connected into a two-dimensional (2D) supramolecular layer via p–p stacking interactions. Complex 6 exhibits a 1D chain which is further extended into a 3D supramolecular network through hydrogen-bonding interactions. The H5L ligand is partially deprotonated in 1–6. The N-donor co-ligands and transition metal ions have important effects on the architectures of 1–6. The photoluminescent properties of 2–4 and the magnetic properties of 1 and 6 were also studied.
关键词： 3,5-Di(3,4-dicarboxylphenyloxy)benzoic acid,Magnetic property,N-donor co-ligand,Photoluminescent property,Transition metal
更新于2025-09-04 15:30:14
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Ultrasonic Studies of Solid Azobenzene-Decorated Polymer Thin Films
摘要： This work investigates the effect of ultrasound on switching of cis azobenzene isomers to their trans counterparts in solid films of methyl methacrylate and methacryloyloxyazobenzene copolymers [P(MMA/MOAB)]. Ultraviolet?visible and 1H nuclear magnetic resonance spectroscopies demonstrate that 46% of the cis isomer converts to the trans form purely by ultrasonic agitation and 46% converts to the trans isomer by localized ultrasound-induced heating effects. Comparative studies of isomerization by ultrasound wave, heat, and visible irradiation show that ultrasound exposure requires a longer time to switch the cis-to-trans conformation. The estimated activation energy for the cis-to-trans conversion in solid polymer films is shown to be comparable to previous values of azobenzene isomerization, indicating that incorporation of the chromophore in a polymeric system affects the kinetics of transition but not the barriers to conformational change.
关键词： azobenzene,nuclear magnetic resonance spectroscopy,polymer thin films,ultrasound,isomerization,ultraviolet?visible spectroscopy
更新于2025-09-04 15:30:14
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Magnetic coupling to the advanced Virgo payloads and its impact on the low frequency sensitivity
摘要： We study the electromagnetic coupling of the Advanced Virgo (AdV) input mirror payload in response to a slowly time-varying magnetic field. As the problem is not amenable to analytical solution, we employ and validate a finite element (FE) analysis approach. The FE model is built to represent as faithfully as possible the real object, and it has been validated by comparison with experimental measurements. The intent is to estimate the induced currents and the magnetic field in the neighbourhood of the payload. The procedure found 21 equivalent electrical configurations that are compatible with the measurements. These have been used to compute the magnetic noise contribution to the total AdV strain noise. At the current stage of development, AdV seems to be unaffected by magnetic noise, but we foresee a non-negligible coupling once AdV reaches the design sensitivity.
关键词： finite element analysis,low frequency sensitivity,gravitational-wave detectors,magnetic coupling,Advanced Virgo
更新于2025-09-04 15:30:14
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Synthesis of gadolinium-based Bi<sub>2</sub>S<sub>3</sub> nanoparticles as cancer theranostics for dual-modality computed tomography /magnetic resonance imaging-guided photothermal therapy
摘要： Development of a safe, efficient and inexpensive multifunctional nanoplatform using a facile approach for multimodal imaging and therapeutic functions becomes more and more practically relevant but challenging. In this work, we demonstrated a novel nanocomposites (Bi2S3-Gd) for computed tomography (CT)/magnetic resonance (MR) imaging-guided photothermal therapy for cancer in vitro. It was achieved by modification of hydrophobic Bi2S3 with a smart amphiphilic gadolinium-chelated ligand. The as-prepared nanocomposites composed of low cost Bi2S3 and gadolinium complexes, showed high stability, excellent biocompatibility and good photostability. It was observed that Bi2S3-Gd nanocomposites can efficiently convert the NIR light into heat, and then suppressed the growth of tumor cells under NIR laser irradiation. Apart from serving as an effective photothermal agent, the as-prepared nanomaterials could induce an efficient contrast enhancement for both CT and MRI imaging at low concentrations of Bi and Gd, rendering more accurate diagnosis. This work suggests the potential of Bi2S3-Gd nanomaterials as a novel multifunctional nanoplatform for CT/MRI imaging-guided photothermal therapy for cancer.
关键词： photothermal therapy,magnetic resonance imaging,Bismuth sulfide,amphiphilic ligand,computed tomography imaging
更新于2025-09-04 15:30:14
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[Institution of Engineering and Technology 12th European Conference on Antennas and Propagation (EuCAP 2018) - London, UK (9-13 April 2018)] 12th European Conference on Antennas and Propagation (EuCAP 2018) - Active Cancellation of Bistatic Scattering of Large Aircraft Using Conformal 4-Port Magnetic Antenna
摘要： Possibilities of the active cancellation of bistatic radar cross section (RCS) of the large aircraft (LA) with help of stealth conformal 4-port magnetic antenna (MA) is considered. The antenna is located in the upper part of the fuselage of an aircraft in a niche under the radar absorbing radome. The antenna is simulated in the form of loop, three-layer ferrite core with four single-turn coils and with excitation ports (in the modes of radiation and scattering). The effect of excitation of the ports on radiation patterns and the cancellation of bistatic RCS of LA?MA system in the range of 10 to 30 MHz is studied. It is shown that the smart inclusion of two or four ports of the active MA in the stealth-mode provides of the deep reduction (more 40 dB relative to aircraft RCS without antenna) of bistatic total RCS in the given angular sectors of observation.
关键词： active cancellation,conformal antenna,ferrite core,large aircraft,radar cross section,magnetic antenna
更新于2025-09-04 15:30:14
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[Institution of Engineering and Technology 12th European Conference on Antennas and Propagation (EuCAP 2018) - London, UK (9-13 April 2018)] 12th European Conference on Antennas and Propagation (EuCAP 2018) - Accuracy Test of Iterative Physical Optics for Analyzing Scattering by Nonperfectly Conducting Bodies Using Impedance Boundary Conditions
摘要： An iterative physical optics has been used to analyze the electromagnetic scattering by electrically large and complex objects with nonperfectly conducting surfaces. The iterative physical optics is near-?eld corrected based on the magnetic ?eld integral equation. By comparing the scatterings computed by the iterative physical optics and multilevel fast mutipole method, the accuracy of the iterative physical optics is investigated.
关键词： magnetic ?eld integral equation (MFIE),near-?eld correction,iterative physical optics (IPO)
更新于2025-09-04 15:30:14
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[Institution of Engineering and Technology 12th European Conference on Antennas and Propagation (EuCAP 2018) - London, UK (9-13 April 2018)] 12th European Conference on Antennas and Propagation (EuCAP 2018) - Mitigating Internal Resonances of the Magnetic-Field Integral Equation via Double-Layer Modeling
摘要： We present a new method to mitigate internal resonances of the magnetic-field integral equation (MFIE) for closed conductors, without combining this equation with the electric-field integral equation (EFIE) that is commonly practiced in the literature. For a given object and its surface, a smaller closed surface is placed inside to create a double layer. This way, the magnetic field intensity is enforced to zero on the inner surface, making the overall solution unique at all frequencies. By eliminating the need for EFIE, the resulting implementation is purely based on MFIE interactions. In addition to its formulation, the initial numerical results of the proposed method on canonical problems are presented.
关键词： internal resonance problem,magnetic-field integral equation,surface integral equations,Boundary element methods
更新于2025-09-04 15:30:14
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Integration of sputter-deposited multiferroic CoFe2O4-BiFeO3 nanocomposites on conductive La0.7Sr0.3MnO3 electrodes
摘要： The structure, magnetic and ferroelectric properties of sputtered epitaxial CoFe2O4-BiFeO3 (CFO-BFO) nanocomposite thin films grown on La0.7Sr0.3MnO3 (LSMO) layers on (001) oriented SrTiO3 (STO) substrates and on STO-buffered Si are described. The as-grown LSMO thin films were smooth and poorly conductive but the resistivity was reduced and the surfaces roughened after annealing. Cosputtered CFO and BFO on STO formed vertically aligned nanostructures consisting of epitaxial spinel CFO pillars within a perovskite BFO matrix, but the rough surface of the annealed LSMO film promoted additional CFO pillar orientations. A reorientation of the CFO magnetic easy axis to an in-plane direction occurred as the LSMO became thicker due to changes in the strain state of the CFO pillars. The LSMO underlayer enabled the ferroelectric response of the BFO to be measured. Nanocomposites were grown onto LSMO/SrTiO3/Si which provides a path towards large scale integration of electrically contacted nanocomposites on Si.
关键词： La0.7Sr0.3MnO3,sputter-deposited,ferroelectric,magnetic properties,nanocomposites,CoFe2O4-BiFeO3,multiferroic
更新于2025-09-04 15:30:14