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A Turn-on MOF-Based Luminescent Sensor for Highly Selective Detection of Glutathione
摘要： Glutathione (GSH), as a key regulator for the redox balance of biological processes, was detected with a metal-organic framework (MOF) (UiO-67-sbdc) fluorescence sensor. The fluorescence of UiO-67-sbdc could be effectively enhanced by GSH via an electronic effect between GSH and the ligand of MOF, thus achieving the recognition of GSH. It is the first attempt to design a MOF-based fluorescent sensor to distinguish GSH from cysteine (Cys). This sensor exhibited short response time (< 120 s), suitable linear range, and high selectivity towards GSH. Further research conducted in serum also showed a quantitative and selective detection of GSH. Thus, the reported UiO-67-sbdc in this work has its application prospect in clinically judging antioxidant capacity of the body.
关键词： turn-on,bio-thiol,Metal-organic frameworks,fluorescence sensor,electronic effect
更新于2025-09-09 09:28:46
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Luminescent MOF nanosheets for enzyme assisted detection of H2O2 and glucose and activity assay of glucose oxidase
摘要： 2D metal-organic framework (MOF) nanosheets have emerged as a novel kind of sensing materials due to the large external surface area and accessible active sites on the surface. In this work, we successfully prepared luminescent MOF nanosheets (In-aip) with thickness of 4 nm by the cation-exchange mediated sonication of a 2D connected anionic MOF. Using In-aip as fluorescent sensor, an enzyme assisted system was established for the analysis of H2O2 with the quenching effect of the oxidation product on its emission. The nanosheet morphology of In-aip ensures its high capture efficiency of unstable intermediate, so high sensitivity was achieved (detection limit = 0.87 μM). With high sensitivity and wide quantitative range, this H2O2 sensing system could be used as a universal platform for the analysis of H2O2 related biomolecules and enzymes. By multi-enzyme cascade catalysis, a detection method of glucose and an activity assay of glucose oxidase were developed based on it. This work is the first example of using luminescent MOF nanosheets to bioanalysis and shows their wide application potential.
关键词： Fluorescence,Nanosheets,H2O2,Metal-organic frameworks,Enzyme assisted sensing
更新于2025-09-09 09:28:46
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Nanocavities cause a stir
摘要： Reactions between gases and liquids are important in industry but are typically slow and difficult to monitor in situ. Elevated temperatures and pressures are often required to increase the efficiency of reactions between immiscible gases and liquids. Now, reporting in Angewandte Chemie International Edition, Xing Yi Ling and colleagues introduce a platform composed of an array of solid nanoparticles coated in a metal–organic framework (MOF) that substantially increases gas–liquid reaction efficiency owing to the formation of interfacial nanocavities. The platform can also be adapted for the in situ monitoring of reactions.
关键词： nanocavities,gas–liquid reactions,metal–organic frameworks,in situ monitoring,solid@MOF
更新于2025-09-09 09:28:46
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Construction of Ce-MOF@COF hybrid nanostructure: Label-free aptasensor for the ultrasensitive detection of oxytetracycline residues in aqueous solution environments
摘要： Porous organic framework (COF) nanomaterials have drawn increasing attention and showed promising potential in the applications of various fields. Nevertheless, its applications in biosensing or biomedical fields are still in the early stage. In this work, we designed and synthesized a series of nanohybrids of COF and Ce-based metal organic framework (Ce-MOF) for the first time as label-free bioplatforms for a sensitive electrochemical aptasensor to detect oxytetracycline (OTC). A novel kinds of Ce-MOF@COF hybrids were prepared by adding different dosages of COF, into the preparation system of Ce-MOF, for which COF was synthesized using melamine and cyanutic acidmonomers through polycondensation (represented by MCA). Basic characterizations revealed that Ce-MOF@MCA nanohybrids not only remained their orignal crystal and chemical structure and features, such as different Ce species containing in Ce-MOF (Ce3+ and Ce4+), various functional amino-groups of MCA, and individual frameworks, but also showed a large specific surface area and interpenetrated morphologies. As a result, the Ce-MOF@MCA hybrid with high content of MCA exhibited high bioaffinity toward the OTC-targeted aptamer, further leading to the incremental detection effect for OTC detection. Among different hybrid-based aptasensors, the Ce-MOF@MCA-based one with an MCA dosage of 500 mg exhibited the lowest limit of detection at 17.4 fg?mL-1 within a wider linearity of the OTC concentration within 0.1–0.5 ng?mL-1. Additionally, the fabricated aptasensor displayed excellent analytical performance with great reproducibility, high selectivity and stability, and acceptable applicability for detecting OTC in various aqueous solutions, including milk, wastewater, and urine samples. This new Ce-MOF@MCA hybrid will become an excellent aptasensors platform for detecting various analytes, such as antibiotics, heavy metal ions, or cancer markers, and it have shown the promissing application potentials in the fields of biomedicine, food safety and environmental monitoring.
关键词： Ce-based metal organic frameworks,Aptamer sensor,Detection of oxytetracycline,Electrochemical impedance spectroscopy,Covalent organic frameworks
更新于2025-09-04 15:30:14
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Synthesis and characterization of luminescent metal–organic frameworks for the selective recognition of Cu2+ cation and Tryptophan
摘要： Three metal-organic frameworks (MOFs), namely, [Mn(CPP)2(H2O)]n (I), [Cd(CPP)2(H2O)]n (II) and {[Zn2(CPP)2(CO3)]·(ClO4)·(H2O)2}n (III) (HCPP = 4'-(4-(4-carboxylphenoxy)-2,2':60,20-terpyridine), were successfully achieved under hydrothermal conditions. The as-synthesized coordination polymers have been characterized by IR spectroscopy, elemental analyses and single crystal X-ray diffraction. Single-crystal X-ray diffraction analyses indicate that compounds ⅠⅠ and ⅡⅡ display isomorphous and isostructural, in which the central metal ions present distorted octahedral configurations. ⅠⅠ and ⅡⅡ feature fascinating 3D frameworks based on p/p and CeH/p interactions between the pyridine rings ligands, while compound ⅢⅢ possesses a 3D net interlinked via C-H/p interactions appertaining CPP ligands. In their 3D frameworks, the {MnN3O3}, {CdN3O3} and {ZnO2N3}e{ZnO2N3} building units are observed, respectively. Luminescent properties of coordination polymer ⅡⅡ and ⅢⅢ demonstrate that they may be acted as fluorescent sensors toward Cu2+ cation and Tryptophan, respectively. Furthermore, investigations on magnetic property reveal that coordination polymer ⅠⅠ presents antiferromagnetic coupling.
关键词： Magnetic analysis,Luminescent recognition,Transition metal ions,Hydrothermal synthesis,Metal organic frameworks
更新于2025-09-04 15:30:14
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An unusual dependency on the hole-scavengers in photocatalytic reductions mediated by a titanium-based metal-organic framework
摘要： The reductive reactions driven by photo-generated electrons on photocatalysts were generally considered to be irrelevant to the employed hole-scavengers. Herein, we report an unexpected dependence of photocatalytic debromination of decabromodiphenyl ether (BDE 209) on the hole-scavengers catalyzed by amine-functionalized MIL-125(Ti). It was found that the debromination only occurred when triethanolamine, rather than the conventional alcohols, was used as the hole-scavenger. Further low-temperature ESR experiments indicate that triethanolamine participates in the formation of the active catalytic Ti (Ⅲ) species, which shuttle the electron to BDE 209, producing reductive debromination products.
关键词： Photocatalysis,Hole-scavengers,BDE 209,Metal-organic frameworks
更新于2025-09-04 15:30:14
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Gas Adsorption and Fluorescent Sensing Properties of Two Porous Lanthanide Metal-Organic Frameworks Based on 3,5-Bis(2-carboxy-phenoxy)-Benzoic Acid
摘要： Two porous isomorphic 3D Eu(Ⅲ)/Nd(Ⅲ) lanthanide metal?organic frameworks (Ln-MOFs), formulated as {[Eu(BCPB)(H2O)(DMF)]·H2O·1.5CH3OH}n (1) and {[Nd(BCPB)(H2O)(DMF)]·2H2O}n (2), have been designed and synthesized by using the tripodal ligand of 3,5-bis(2-carboxy-phenoxy)-benzoic acid (H3BCPB) under solvothermal condition. Complexes 1 and 2 display 3D (3,6)-c net with the point symbol of {4.62}2{42.610.83}. Furthermore, fluorescent measurements showed 1 has highly selective detection for Fe3+ and CrO4 2- ions in aqueous solution, which shows that it acts as a chemical sensor for detecting Fe3+/CrO4 2- in aqueous solution. Meanwhile, gas adsorption properties of 1 and 2 have also been studied at different temperatures for N2, CH4 and CO2.
关键词： Fluorescent Properties,Adsorption Properties,Lanthanide Metal?Organic Frameworks,3,5-Bis(2-Carboxy-Phenoxy)-Benzoic Acid
更新于2025-09-04 15:30:14
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Bimetallic metal organic frameworks: Magnetically separable heterogeneous catalyst for efficient organic transformation and photocatalytic dye degradation
摘要： A new bimetallic MOF (BMOF) has been synthesized using iron and zinc as inorganic metal nodes and 1-4, benzenedicarboxylic acid (BDC) as organic linker molecule. BMOF was confirmed with Single crystal X-ray diffraction (SCXRD), X-ray photoelectron spectroscopy (XPS), Transmission electron microscopy-high angle annular dark-field imaging (TEM-HAADF), Field emission scanning electron microscopy-energy dispersive x-ray analysis (FESEM-EDX), Vibrating sample magnetometer (VSM) and inductively coupled plasma-mass spectrometry (ICP-MS) analysis. The synthesized BMOF shows excellent optical and magnetic properties. BMOF acts as a heterogeneous catalyst and show high catalytic activity towards bis(indolyl)methane synthesis and photocatalytic degradation of methylene blue (MB) under visible light illumination.
关键词： Metal-organic frameworks,dye degradation,Bis(indolyl)methanes,photocatalysis
更新于2025-09-04 15:30:14
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Bismuth(III) based Metal Organic Frameworks: Luminescence, Gas Adsorption, and Antibacterial Studies
摘要： BiIII-MOFs 1–4 were prepared via solvothermal method using four organic linkers; 2-mercapto-3-methyl-4-thiazoleacetic acid (H2MMTA), 2,6-naphthalenedicarboxylic acid (2,6-NDA), 4,6-dihydroxy-2-mercaptopyrimidine (H2DMP), and 4-mercaptobenzoic acid (H2MBA), respectively. The resulting MOFs were structurally/morphologically characterized by UV/Vis, AAS/ICP-MS, Fourier transform infrared spectroscopy (FT-IR), 1H NMR, thermogravimetric analysis (TGA), scanning electron microscopy (SEM), and powder X-ray diffraction technique. All these MOFs showed good luminescence properties exhibiting blue luminescence. N2 gas adsorption isotherms of 1–4 confirmed the porosity of these frameworks. In order to evaluate the effect of metal ion upon chelation, the free organic linkers and respective MOFs were screened for their antibacterial potential against some pathogenic bacteria and appreciable activity was observed.
关键词： Metal organic frameworks,Luminescence,Bismuth,Bidentate ligands
更新于2025-09-04 15:30:14
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Interface-induced enhanced electromagnetic wave absorption property of metal-organic frameworks wrapped by graphene sheets
摘要： Most of metal–organic frameworks (MOFs) themselves have low electrical conductivities, leading to bad electromagnetic wave (EMW) absorption properties. Herein we found that the EMW absorption property of zeolitic imidazolate frameworks-8 (ZIF-8) particles was improved unexpectedly after coupling them with graphene sheets. Experimental results and theoretical calculations indicated that well-defined interfaces between ZIF-8 and the graphene sheets were crucial to the improvement of EMW absorption property. Our strategy presented here may open a new way for designing other MOFs based hybrids for high-performance EMW absorbers.
关键词： Porous structure,Graphene-organics composites,Metal–organic frameworks,Electromagnetic wave absorption,Multiple interfaces
更新于2025-09-04 15:30:14