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Src Kinase Controls Signaling Pathways In Sensory Neuron Triggered By Low-Power Infrared Radiation
摘要： Low-power (non-thermal) infrared (IR) radiation with the wavelength of 10.6 μm activates the Na,K-ATPase transducer function in sensory neurons, which is manifested in decrease of NaV1.8 channel voltage sensitivity at the cellular membrane level and in inhibition of growth of chick embryo dorsal root ganglia neurites at the tissue level. It is shown that the effect of low-power IR radiation is totally blocked by a specific Src kinase inhibitor PP2. Upon irradiation on the background of PP2, the effective charge of NaV1.8 channel activation gating system does not differ from its control value in patch-clamp experiments, and the area index of sensory ganglia neurites growth remains unchanged as compared to the control in organotypic tissue culture. The data obtained demonstrate that Src kinase is involved in intracellular signaling pathways triggered by CO2 laser low-power IR radiation by the transducer-activated mechanism. This is the first indication that in primary sensory neuron the signals of low-power IR radiation are sensed, amplified and transduced by the Na,K-ATPase/Src complex and not by G proteins.
关键词： Src kinase,infrared radiation,Na,K-ATPase,organotypic nerve tissue culture,NaV1.8 channels,sensory neuron,patch-clamp method
更新于2025-11-21 11:24:58
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A thin-layer dielectric and metamaterial unit-cell stack loaded miniaturized SRR-based antenna for triple narrow band 4G-LTE applications
摘要： This article presents the design of a miniaturized dual-band antenna for long-term evolution (LTE) application is presented. In the basic antenna design, split ring resonator was loaded in the radiating plane of the patch and frequency of resonance was further modified with the help of E-shaped stub. The antenna has been fabricated using FR-4 substrate and the measured dual bands at 2.11 and 2.665 GHz are found in a close match with the simulated data. By placing a thin dielectric resonator of permittivity εr = 10.2 and thickness of 1.27 mm, two closely spaced narrow bands are obtained at 2.217 and 2.28 GHz. A novel metamaterial unit-cell having near-zero refractive index is designed and mounted above the dielectric resonator. This stack configuration generates triple narrow frequency band in the LTE 2 GHz spectrum range. The overall size of the proposed antenna is 20 × 25 mm2.
关键词： triple band,split ring resonator,thin layer dielectric resonator,reflection coefficient,patch,unit-cell
更新于2025-09-23 15:23:52
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A dual-band efficient circularly polarized rectenna for RF energy harvesting systems
摘要： A multilayered circularly polarized (CP), dual-band, stacked slit-/slotted-patch antenna with compact size and with compact rectifier is offered for RF energy harvesting systems. The compact dual-band CP antenna size is able to achieve by stacking slotted-circular-patch (SCP) on the substrate above the tapered-slit-octagon patch (TSOP). Dual-band CP radiation is realized by stacking the SCP on the TSOP and the microstrip feedline with metallic-via to SCP. Eight-tapered-slit with length difference of 6.25% are embedded along the octagonal directions symmetrically on the TSOP from the patch's center and two unequal size circular slots are embedded in diagonal axis onto SCP to produce dual-orthogonal modes with almost equal magnitude for CP waves. The designed antenna is realized measured gain of greater than 5.2 dBic across the band (0.908-0.922 GHz) with maximum gain of 5.41 dBic at 0.918 GHz and gain of greater than 6.14 dBic across the band (2.35-2.50 GHz) with maximum gain of 7.94 dBic at 2.485 GHz. An overall antenna volume is 0.36λo × 0.36λo × 0.026λo (λo is free space wavelength at 0.9 GHz). A compact composite right-/left-handed (CRLH) based rectifier with dual-band at 0.9 and 2.45 GHz is designed, prototyped, and measured. The right-handed (RH) part of the CRLH transmission line (TL) is formed by a microstrip line. The left-handed (LH) part of the CRLH-TL is formed by lumped components. The measured RF-DC conversion efficiency is 43% at 0.9 GHz and 39% at 2.45 GHz with rectifier size of 0.18λo × 0.075λo × 0.0002λo at 0.9 GHz.
关键词： slotted-patch,stacked antenna,energy harvesting,rectenna,rectifier,circular polarization,dual-band
更新于2025-09-23 15:23:52
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A dual-band circularly polarized microstrip patch antenna with a cross shaped slot for 0.92/2.45 GHz RFID applications
摘要： A double-band circularly polarized (CP) patch antenna is presented. It is a round patch antenna with a cross-shape slot. Furthermore, it radiates wide beam CP waves at two radio-frequency identification (RFID) bands: 920 MHz and 2.45 GHz. Slightly oblate round patch antennas generally radiate CP waves and have resonant frequencies at two or more harmonic bands. To radiate wide beam CP waves at two bands, a cross-shape slot was made on a round patch antenna in this study. As a result, the cross-shape slot has made it possible for a 920 MHz round patch antenna to simultaneously radiate wide beam CP waves at 2.45 GHz which is higher than a harmonic frequency.
关键词： circularly polarized,RFID,cross shaped slot,double-band,patch antenna
更新于2025-09-23 15:23:52
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[IEEE 2018 International Conference on Microwave and Millimeter Wave Technology (ICMMT) - Chengdu, China (2018.5.7-2018.5.11)] 2018 International Conference on Microwave and Millimeter Wave Technology (ICMMT) - A Low-Profile Dual-Polarized Patch Antenna with Bandwidth Enhanced by Stacked Parasitic Elements
摘要： In this paper, a low-profile dual-linear polarized patch antenna composed of two stacked substrates, one air gap layer, and one grounded substrate is proposed. There is a feeding patch element with two excited probes placed on the top side of the grounded substrate, and one parasitic patch element and a 2×2 parasitic array patch elements printed on the lower and upper stacked substrate, respectively. The T- and rectangular slots and T-stubs are employed on/near the orthogonal axis of the patches for the impedance matching and two orthogonal polarizations improvement. Furthermore, four stacked complementary split-ring resonators (CSRRs) are loaded in the two stacked substrates mainly to adjust the impedance matching and port isolation with an induced dual-polarized resonance. Thanks to the stacked patches and CSRRs, an enhanced impedance bandwidth from 1.2% to 7.4% was achieved by the introduced three additional dual-polarized resonances. Simulated results show the antenna has a impedance bandwidth across 2.362-2.544 GHz (fractional bandwidth 7.4%), a maximum realized gain of 10 dBi, and port isolation better than 22 dB over the operational bandwidth. In addition, a low profile of 0.048λ0 (where λ0 is the free-space wavelength at the central frequency) is maintained in the proposed antenna.
关键词： Dual-polarized,stacked parasitic elements,low-profile,multilayer patch antenna
更新于2025-09-23 15:23:52
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Quick visualization of neurons in brain tissues using an optical clearing technique
摘要： Neurons are classified into several morphological types according to the locations of their somata and the branching patterns of their axons and dendrites. Recent studies suggest that these morphological features are related to their physiological properties, including firing characteristics, responses to neuromodulators, and wiring patterns. Therefore, rapid morphological identification of electrophysiologically recorded neurons promises to advance our understanding of neuronal circuits. One of the most common anatomical cell identification methods is neuronal reconstruction with biocytin delivered through whole-cell patch-clamp pipettes. However, conventional reconstruction methods usually take longer than 24 h and limit the throughput of electrophysiological experiments. Here, we developed a quick, simple cell reconstruction method by optimizing the tissue clearing protocol ScaleSQ. We found that adding 200 mM NaCl almost entirely prevented tissue swelling without compromising optical clearing ability. This solution, termed IsoScaleSQ, allowed us to increase the transparency of the gray matter of 500-μm-thick slices within 30 min, meaning that the total time required to reconstruct whole-cell recorded neurons was reduced to 1 h. This novel method will improve the efficacy and effectiveness of electrophysiological experiments linked to cell morphology.
关键词： Optical clearing,Isotropic,Visualization,Patch-clamp recording,ScaleSQ
更新于2025-09-23 15:23:52
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Oxygen Saturation Measurements from Green and Orange Illuminations of Multi-Wavelength Optoelectronic Patch Sensors
摘要： Photoplethysmography (PPG) based pulse oximetry devices normally use red and infrared illuminations to obtain oxygen saturation (SpO2) readings. In addition, the presence of motion artefacts severely restricts the utility of pulse oximetry physiological measurements. In the current study, a combination of green and orange illuminations from a multi-wavelength optoelectronic patch sensor (mOEPS) was investigated in order to improve robustness to subjects’ movements in the extraction of SpO2 measurement. The experimental protocol with 31 healthy subjects was divided into two sub-protocols, and was designed to determine SpO2 measurement. The datasets for the first sub-protocol were collected from 15 subjects at rest, with the subjects free to move their hands. The datasets for the second sub-protocol with 16 subjects were collected during cycling and walking exercises. The results showed good agreement with SpO2 measurements (r = 0.98) in both sub-protocols. The outcomes promise a robust and cost-effective approach of physiological monitoring with the prospect of providing health monitoring that does not restrict user physical movements.
关键词： green and orange illuminations,optoelectronic patch sensor (mOEPS),oxygen saturation (SpO2),physical movement,pulse oximetry
更新于2025-09-23 15:23:52
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Electrically tuned microwave CP cross slot patch antenna using liquid crystal technology
摘要： The rapid progress in material science and electronic technology is great possibility in designing reconfigurable wireless devices which are frequency tunable, flexible and consume low energy. In this paper, the anisotropic propriety of a new liquid crystal mixture 'GT3-23001' in their nematic phase are exploited for designing tunable circular polarized cross slot patch antenna for WLAN applications. Reconfiguration of frequency response is controlled through an electrical external command. The proposed reconfigurable antenna based on liquid crystal satisfies a continuous frequency tuning of 15.83% with a global bandwidth of around 467.92 MHz (19.5%). to validate this novel mixture of liquid crystal, the simulated results are compared with the measured data and a good agreement is noticed.
关键词： liquid crystal mixture,Material science,tunable patch,circular polarized,reconfigurable,frequency tuning
更新于2025-09-23 15:23:52
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[IEEE 2018 IEEE Conference on Antenna Measurements & Applications (CAMA) - Va?ster?s (2018.9.3-2018.9.6)] 2018 IEEE Conference on Antenna Measurements & Applications (CAMA) - Pattern Reconfigurable Antenna Using A Functional Material for MMW Application
摘要： This paper introduces a novel reconfigurable antenna for controlling radiation beam direction by using integrated phase-change material (PCM). A PCM GeTe-based parasitic patch considered as a switchable element between insulator and conductive states is applied to operate with a driven patch radiator. The direction of the radiation pattern of the antenna can be tilted by changing the state of the GeTe-based patch from its insulator to conductive state. Obtained result shows that the proposed technique is effective to control the beam direction of the antenna. Around a 400 titled angle is achieved by the insulator-to-conductor activation of the GeTe patch which can be realized by an optical source, making the antenna simple and compact without extra bias circuit. Hence, the antenna is suitable for millimeter-wave applications.
关键词： pattern reconfigurable,millimeter wave application,GeTe-based parasitic patch
更新于2025-09-23 15:23:52
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[IEEE 2018 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) - Honolulu, HI (2018.7.18-2018.7.21)] 2018 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) - Remote Heart Rate Measurement from RGB-NIR Video Based on Spatial and Spectral Face Patch Selection
摘要： In this paper, we propose a novel heart rate (HR) estimation method using simultaneously recorded RGB and near-infrared (NIR) face videos. The key idea of our method is to automatically select suitable face patches for HR estimation in both spatial and spectral domains. The spatial and spectral face patch selection enables us to robustly estimate HR under various situations, including scenes under which existing RGB camera-based methods fail to accurately estimate HR. For a challenging scene in low light and with light fluctuations, our method can successfully estimate HR for all 20 subjects (±3 beats per minute), while the RGB camera-based methods succeed only for 25% of the subjects.
关键词： spectral domain,remote sensing,spatial domain,face patch selection,heart rate estimation,RGB-NIR video
更新于2025-09-23 15:23:52