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[IEEE 2018 IEEE International Conference on Imaging Systems and Techniques (IST) - Krakow, Poland (2018.10.16-2018.10.18)] 2018 IEEE International Conference on Imaging Systems and Techniques (IST) - A Novel MRA-Based Framework For Detecting Correlation Between Cerebrovascular Changes and Mean Arterial Pressure
摘要： Systemic hypertension is a signi?cant contributor for strokes and cognitive impairment and is a leading cause of mortality in the USA. Changes in cerebral vascular diameter and cerebral perfusion pressure have been reported to precede elevation of systemic blood pressures. A novel, non-invasive Time-of-Flight - Magnetic Resonance Angiography (TOF-MRA) based framework for detection of cerebrovascular changes is presented. The proposed framework analyzes brain TOF-MRA data to quantify changes in cerebral vascular diameter and cerebral perfusion pressure. The framework has three major steps: 1) Adaptive segmentation to extract large and small diameter cerebral vessels from TOF-MRA images using both appearance and 3-D spatial information of the vascular system; 2) Estimation of the Cumulative Distribution Function (CDF) of the 3-D distance map of the cerebral vascular system, which represents the changes in diameter of the 3-D vascular system ; and 3) Statistical and correlation analysis that measured the effect of Mean Arterial Pressure (MAP) on blood vessels’ diameter changes. The ef?cacy of the framework was evaluated using MRA images and blood pressure (BP) measurements obtained from 15 patients (M=8, F=7, Age=49.2±7.3 years) on Day 0 and Day 700. The framework had a dice similarity coef?cient of 92.23%, a sensitivity of 94.8% and a speci?city of ～ 99% in detecting elevated vascular pressures compared to ground truth. Statistical analysis demonstrated an inverse relationship between blood vessels diameters and MAP. This correlation was valid for both upper (above the circle of Willis) and lower (circle of Willis and below) sections of the brain. The proposed methodology may be used to quantify changes in cerebral vasculature and cerebral perfusion pressure non-invasively through MRA image analysis, which may be a useful tool for clinicians to optimize medical management of pre-hypertension and hypertension.
关键词： Vessel Diameter,Skull Stripping,CDF,Automatic Segmentation,Mean Arterial Pressure,Blood Vessels,MRA,Hypertension,Median Vascular Radius
更新于2025-09-23 15:22:29
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Simple imaging for the diamond anvil cell: Applications to hard-to-reach places
摘要： The employment of high-pressure gases as a pressure-transmitting medium, sample, or reactant for diamond anvil cell experiments is widespread. As a pressure transmitter, high-pressure gases are crucial to forming quasi-hydrostatic compression atmospheres for samples inside the uniaxially driven cell. We describe an optical design for forming high-resolution images of the gasket and sample chamber of the diamond anvil cell under high gas pressures in a gas loading apparatus. Our design is simple, is of low-cost, and may be easily adapted to suit gas loading apparatus of any design, as well as other common hard-to-reach environments in diamond anvil cell experiments, i.e., those with large stand-off distances, such as cryostats.
关键词： optical design,high-pressure gases,gas loading apparatus,diamond anvil cell,imaging
更新于2025-09-23 15:21:21
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Atomistic modeling of the infrared response of fullerenes under hydrostatic pressure
摘要： The anharmonic infrared spectrum of individual C60 and C70 fullerenes under hydrostatic pressure was theoretically computed by means of atomistic simulations. Using a tight-binding model for the fullerenes and a simple particle-based pressure-transmitting fluid, the structural and vibrational properties were determined at room temperature and up to 20 GPa. All properties generally exhibit relative variations that are linear with increasing pressure, but whose magnitude can be comparable to pure thermal effects. The bond length contraction usually agrees with existing results, and for C70 our approach manages to reproduce the occasionally negative pressure coefficient found for some low-frequency modes in experiments.
关键词： fullerenes,pressure effects,infrared spectroscopy
更新于2025-09-23 15:21:21
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Fiber Optic Fabry-Perot Pressure Sensor with Embedded MEMS Micro-Cavity for Ultra-High Pressure Detection
摘要： we demonstrate a fiber-optic Fabry-Perot pressure sensor with embedded MEMS micro-cavity for ultra-high pressure detection. The embedded type structure (ETS) is first proposed and analyzed to meet the requirements of ultra-high pressure detection. The geometry parameters of sensor have been optimized by analyzing mechanical and optical characteristics. From the analysis results based on the ETS, an ultra-high pressure sensor is fabricated and experimentally demonstrated for ultra-high pressure detection. The ultra-high pressure experiment illustrated response relationship between the absolute phase and pressure in the range of 2~120MPa, and full-scale errors less than 0.079%F.S. at room temperature. The other characteristics index of sensor, such as pressure sensitivity, hysteresis error, temperature’s influence factor are superior to rad/ ℃ . The transient response time of system is 0.27s. The sensor can be used for ultra-high pressure detections, which is necessary in deep-sea and oil exploration.
关键词： Pressure detection,Fabry-Perot,Fiber optic sensor
更新于2025-09-23 15:21:21
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In situ high-pressure spectroscopic studies using moissanite (4H-SiC) anvils
摘要： We examined the Raman scattering and IR absorption spectroscopy of 4H-SiC and its performance as an anvil material for high-pressure UV-visible absorption spectroscopic measurements. The first- and second-order Raman peaks of 4H-SiC and diamond do not coincide. 4H-SiC does not have obvious signals from 2330-5000 cm-1, suggesting that 4H-SiC anvils are beneficial for high-pressure studies of samples whose Raman signals locate in the region of diamond. Above 1800 cm-1, the transmitted signal of 4H-SiC in the IR absorption spectra, measured through 4.6 mm thickness is much higher than that of type IIa diamond. An in situ high-pressure UV-visible absorption spectroscopy study on CdI2 was carried out up to 28.0 GPa using 4H-SiC anvil cells (4H-SAC) with a 400 μm culet and the acquired band gap narrowed with increasing pressure. These results show that 4H-SiC has an excellent performance in high-pressure spectroscopic studies.
关键词： IR absorption spectroscopy,high-pressure,UV-visible absorption spectroscopy,Raman spectroscopy,4H-SiC
更新于2025-09-23 15:21:21
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Non-Invasive Detection of Mechanical Alternans Utilizing Photoplethysmography
摘要： Background and Significance: Mechanical alternans (MA) is a biomarker associated with mortality and life-threatening arrhythmias in heart failure patients. Despite showing prognostic value, its use is limited by the requirement of measuring continuous blood pressure (BP), which is costly and impractical. Objective: To develop and test, for the first time, non-invasive MA surrogates based on photoplethysmography (PPG). Methods: Continuous BP and PPG were recorded during clinical procedures and tests in 35 patients. MA was induced either by ventricular pacing (Group A, N=19) or exercise (Group B, N=16). MA was categorized as sustained or intermittent if MA episodes were observed in at least 20 or between 12 to 20 consecutive beats, respectively. Eight features characterizing pulse morphology were derived from the PPG and MA surrogates were evaluated. Results: Sustained alternans was observed in 9 patients (47%) from Group A, whereas intermittent alternans was observed in 13 patients (68%) from Group A and in 10 patients (63%) from Group B. The PPG-based MA surrogate showing the highest accuracy, V’M, was based on the maximum of the first derivative of the PPG pulse. It detected both sustained and intermittent MA with 100% sensitivity and 100% specificity in Group A and intermittent MA with 100% sensitivity and 83% specificity in Group B. Furthermore, the magnitudes of MA and its PPG-based surrogate were linearly correlated (R2=0.83, p<0.001). Conclusion: MA can be accurately identified non-invasively through PPG analysis. This may have important clinical implications for risk stratification and remote monitoring.
关键词： Blood pressure (BP),cardiac alternans,photoplethysmography (PPG),hemodynamic instabilities,mechanical alternans (MA)
更新于2025-09-23 15:21:21
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Design of a Wide Ranging Highly Sensitive Pressure Sensor Based on Two-Dimensional Photonic Crystals
摘要： A highly sensitive pressure sensor operating over a wide pressure range based on two-dimensional photonic crystals having a Mach-Zehnder interferometer structure has been developed. The plane wave expansion method (PWE) is used to determine the device operating wavelength range. The finite difference time domain method (FDTD) is used to calculate the device characteristic parameters such as the resonant frequency, the power transmission, and the sensitivity. The present sensor has two wide frequency ranges, a high sensitivity to refractive index changes and the highest detectable sensitivity pressure so far reported in the literature, that is, 25.06 nm/GPa. The present device has high and constant transmission power all over the entire pressure range 0 to 10 GPa. This is of practical importance since the constraints imposed on the sensing system (the light source and the photodetector) are the same.
关键词： Power transmission,Sensitivity,Mach-Zehnder interferometer,Pressure sensor,2-D photonic crystals,FDTD
更新于2025-09-23 15:21:21
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Sensitive dual sensing system for oxygen and pressure based on deep ultraviolet absorption spectroscopy
摘要： In this study, a highly sensitive monitoring system for dual sensing of oxygen and pressure has been developed. The absorption of oxygen in the wavelength range of 186–196 nm was observed and the corresponding absorption cross-section of oxygen in this band was achieved. An approach based on differential optical absorption spectroscopy was used to describe the concentration of oxygen. The detection limit of oxygen was determined to be 150 ppm per meter. No relation between pressure and oxygen absorption line shape in the related wavelength band was confirmed. Based on the absorption of oxygen, pressure detection was realized and a detection limit of 180 Pa was obtained. A dual sensing system for oxygen and pressure was constructed.
关键词： Pressure,Oxygen,Absorption spectroscopy,Ultraviolet,Dual sensing
更新于2025-09-23 15:21:21
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Flexible electrochromic tungsten/iron mixed oxide films synthesized by an atmospheric pressure plasma jet
摘要： Flexible electrochromic organo-tungsten- iron oxide (WFexOyCz) films are rapidly deposited onto flexible (60 Ω/□ polyethylene terephthalate/indium tin oxide; PET/ITO) substrates by a low temperature-atmospheric pressure-plasma polymerization method with an atmospheric pressure plasma jet (APPJ) for a short exposed duration of 48 s. The precursor vapors of tungsten hexacarbonyl [W(CO)6] and biscyclopentadienyl iron [ferrocene; Fe(C5H5)2] are mixed with O2 gases at various gas flow rates, injected into air plasma jet and sprayed onto PET/ITO substrates at room temperature (~23oC) and at atmospheric pressure (1.013 × 105 Pa). Flexible electrochromic WFexOyCz films are synthesized with a specific addition of oxygen gases with superior lithium electrochromic properties as demonstrated by a potential sweep alternating between -1 V and 2 V at a scan rate of 40 mV/s in a 1 M LiClO4-propylene carbonate electrolyte. With amorphous WFexOyCz films produced with an APPJ by adding oxygen gases at a specific flow rate of 0.5 sccm, a high value in oxygen deficiency up to 0.189 allows more Li+ ions to intercalate into and deintercalate out of the film. Significant coloration and bleaching are proven by the high values in optical transmittance modulation (ΔT) of up to 70.3%, optical density (ΔOD) up to 0.77 and color efficiency (η) up to 61.3 cm2/C, at a wavelength of 800 nm, respectively.
关键词： Electrochromic materials,Iron oxide,Tungsten oxide,Flexible electrochromic film,Atmospheric pressure plasmas,Plasma polymerization
更新于2025-09-23 15:21:21
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Application of rubrene air-gap transistors as sensitive MEMS physical sensors
摘要： Micro electromechanical systems (MEMS) made of organic materials have attracted efforts on development a new generation of physical, chemical and biological sensors, for which the electromechanical sensitivity is the current major concern. Here, we present an organic MEMS made of a rubrene single crystal air-gap transistor. Applying mechanical pressure on the semiconductor results in high variations of drain current: an unparalleled Gauge factor above 4000 has been measured experimentally. Such a high sensitivity is induced by the modulation of charge injection at the interface between the gold electrode and the rubrene semiconductor as an unusual transducing effect. Applying these devices to the detection of acoustic pressure shows that force down to 230 nN can be measured with a resolution of 40 nN. This study demonstrates that MEMS based on rubrene air-gap transistors constitute a step forward to the development of high performance flexible sensors.
关键词： crystal,charge injection,organic MEMS,pressure sensor,air-gap transistor,OFET,rubrene
更新于2025-09-23 15:21:21